3-Ethynylimidazo[1,2-b]pyridazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 943320-61-4 |
| Product name | 3-Ethynylimidazo[1,2-b]pyridazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Ethynylimidazo[1,2-b]pyridazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Ethynylimidazo[1,2-b]pyridazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Ethynylimidazo[1,2-b]pyridazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Lead compounds for small-molecule kinase inhibitors | Used in structural modification and structure–activity relationship (SAR) studies; aryl or alkynyl side chains are introduced via Suzuki or Sonogashira coupling |
| Agrochemical R&D | Molecular scaffold for novel insecticides | Serves as a core heterocyclic structure in constructing candidate molecules targeting the insect nicotinic acetylcholine receptor (nAChR) |
| Materials Science | Dopant component in organic light-emitting diode (OLED) hole-transport layers | Codeposited with TPD or NPB via vacuum thermal evaporation to tune carrier mobility and energy-level alignment |
Manufacturing Quality Control of 3-Ethynylimidazo[1,2-b]pyridazine
| Test Item | Common Testing Methods | Method Summary |
|---|---|---|
| Identity | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) Mass Spectrometry (MS) |
Confirm whether the compound structure is 3-alkynyl imidazo[1,2-b]pyridazine by analyzing characteristic IR absorption peaks, ¹H NMR chemical shifts and coupling constants, as well as molecular ion and fragment ions in mass spectrometry. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column with methanol/acetonitrile-water or buffer systems as mobile phase, and a UV detector (typically at 254 nm or set according to maximum absorption wavelength), the content of the main component is quantitatively analyzed using external standard method or area normalization method to determine purity. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) | Under the same or optimized conditions as for assay, related substances such as process impurities and degradation products are separated and detected. These impurities are controlled by limit tests using the standard substance self-comparison method or the main component self-comparison method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, headspace or direct injection GC-FID methods are used to detect residual organic solvents (e.g., dichloromethane, methanol, acetonitrile, DMF) that may remain from the synthesis process. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Loss on Drying at Atmospheric Pressure | Determine the percentage loss in sample weight due to moisture or other volatile components by drying to constant weight at a specified temperature (e.g., 105°C). |
| Sulfated Ash / Residue on Ignition | High-Temperature Incineration Method | The sample is carbonized and then ignited in a high-temperature furnace at 700–800°C to determine the amount of inorganic residue, used to assess residual inorganic salts or metal catalysts. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, AAS or the more sensitive ICP-MS is used to detect trace levels of heavy metal elements such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial standards or ICH Q3D requirements. |
| Water Content | Karl Fischer Titration | Using volumetric or coulometric Karl Fischer titration to accurately measure trace water content in samples; suitable for quality control of active pharmaceutical ingredients sensitive to moisture. |
Technical Specifications of 3-Ethynylimidazo[1,2-b]pyridazine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Ethynylimidazo[1,2-b]pyridazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Ethynylimidazo[1,2-b]pyridazine
Safety Information of 3-Ethynylimidazo[1,2-b]pyridazine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Ethynylimidazo[1,2-b]pyridazine
Industrial 3-Ethynylimidazo[1,2-b]pyridazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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