China Factory Direct
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| CAS number | 94838-59-2 |
| Product name | [2-(4-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing linkers in targeted protein degradation chimeras (PROTACs) | Used in solid-phase or solution-phase synthesis to construct linker units containing an aniline-ethyl-malonic acid structure via coupling of the amino group with activated carboxylic acid derivatives (e.g., NHS esters) |
| Organic Synthesis | Multifunctional synthon providing a protected amino group and a deprotectable carboxylic acid functionality | The tert-butyl ester group is cleaved with trifluoroacetic acid (TFA) to yield the free carboxylic acid; the aromatic primary amino group participates in diazotization, acylation, alkylation, and other reactions to build heterocycles or coupling products |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identity | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirms compound structure by identifying characteristic functional groups (e.g., amino, ester, tert-butyl) through their infrared absorption peaks. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyzes chemical shifts, integration areas, and coupling constants of hydrogen atoms to verify molecular structure and purity. | |
| Mass Spectrometry (MS or HRMS) | Determines molecular ion and fragment ions to confirm molecular weight and elemental composition; high-resolution MS can verify molecular formula. | |
| Assay | High-Performance Liquid Chromatography with UV detection (HPLC-UV) | Uses a reversed-phase C18 column and UV detector (typically 210–260 nm) to quantify the main component; concentration calculated using external standard method. |
| Gas Chromatography with FID/MS detection (GC-FID/MS)* | If the compound is thermally stable and volatile, GC may be used for assay (less common for highly polar compounds). | |
| Related Substances / Impurities | High-Performance Liquid Chromatography with DAD/UV detection (HPLC-DAD/UV) | Employs gradient elution to separate the main peak from potential impurities (e.g., starting materials, intermediates, degradation products); DAD detector aids in peak purity assessment. |
| Residual Solvents | Headspace Gas Chromatography with Flame Ionization Detection (HS-GC-FID) | Detects organic solvents (e.g., methanol, ethanol, dichloromethane, toluene) that may remain from synthesis or purification processes, in accordance with ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Accurately measures water content using volumetric or coulometric methods; suitable for moisture-sensitive organic compounds. |
| Melting Point | Melting Point Apparatus | Determines the temperature range at which the compound melts; serves as a physical constant for preliminary identification and purity evaluation (higher purity results in a narrower melting range). |
| Appearance and Color | Visual Comparison | Observes whether the sample is a white to off-white solid, free from foreign matter or abnormal coloration, meeting pharmacopoeial or internal specifications. |
| pH (if prepared as solution) | pH Meter | Measures the pH of a solution or suspension at a specified concentration to assess the influence of acidic or basic impurities (applicable for soluble salt forms). |
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow powder or crystals |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.