S-1-CBZ-3-Hydroxy-piperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 94944-69-1 |
| Product name | S-1-CBZ-3-Hydroxy-piperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for S-1-CBZ-3-Hydroxy-piperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk S-1-CBZ-3-Hydroxy-piperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of S-1-CBZ-3-Hydroxy-piperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of chiral drug intermediates for R&D of antidepressant and antipsychotic agents | Preparation of the (R)-enantiomer via asymmetric synthesis or chiral resolution, serving as a key intermediate in multistep reactions |
| Organic Synthesis | Precursor to chiral catalysts or ligands for constructing complex molecular architectures | Used as a chiral auxiliary in transition metal-catalyzed reactions to enhance stereoselectivity |
| Biochemical Research | Probe molecule for studying neurotransmitter receptor binding mechanisms | Structurally modified with fluorescent or isotopic labels for receptor binding assays and pharmacological studies |
Manufacturing Quality Control of S-1-CBZ-3-Hydroxy-piperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | (R)-Enantiomeric Excess | Chiral HPLC |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, ethyl acetate, toluene) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to quantitatively determine water content via electrochemical endpoint detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residual Palladium | ICP-OES | Quantification of residual Pd catalyst after microwave-assisted acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-CBZ analog, epimer, hydrolysis products) by gradient reverse-phase HPLC with UV detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate; onset and range indicate crystallinity and purity. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at sodium D-line (589 nm) to confirm chiral integrity and batch-to-batch consistency. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering principles to determine D10, D50, D90 values. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms per USP <61> using filtration, membrane transfer, and incubation on TSA agar. |
Technical Specifications of S-1-CBZ-3-Hydroxy-piperidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Optical Rotation | +15.0 to +22.0° (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78.0 to 82.0°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of S-1-CBZ-3-Hydroxy-piperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of S-1-CBZ-3-Hydroxy-piperidine
Packaging of S-1-CBZ-3-Hydroxy-piperidine
Industrial S-1-CBZ-3-Hydroxy-piperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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