China Factory Direct
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| CAS number | 950670-18-5 |
| Product name | 3-Bromo-5-fluoropyridine-2-carbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of novel insecticidal intermediates | Bromination and cyanation of the pyridine ring via nucleophilic substitution, followed by fluorination |
| Pharmaceuticals | Synthesis of anticancer and antiviral drug intermediates | Used as a key intermediate for constructing complex heterocyclic structures in multistep organic synthesis |
| Polymers | Precursor for functional monomers or crosslinking agents | Incorporated into polymer backbones via coupling reactions (e.g., Suzuki, Negishi) to enhance material performance |
| Fine Chemicals | Synthesis of fluorescent dyes or optoelectronic material intermediates | Leverages its nitrogen-containing heterocyclic structure and multiple functional groups in the synthesis of photoluminescent materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification relies on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., acetone, methanol, toluene) by gas chromatography with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Hg, Ni) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation with carbonate/bicarbonate eluent. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion at 600-700 C followed by weighing of the cooled crucible contents. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined standards (e.g., white to off-white crystalline powder). |
| Bulk Density | Tap Density Tester | Measures mass per unit volume after standardized tapping (e.g., 100 taps) per USP <616> to assess flow and packing behavior. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution by analyzing angular scattering pattern of laser light passed through dispersed sample in air or liquid medium. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light source to confirm chiral integrity and absence of racemization (though compound is achiral, verifies no chiral contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=99.0% (GC-MS) |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 82–86°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.