China Factory Direct
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| CAS number | 952234-36-5 |
| Product name | 1H-Imidazole-1-sulfonyl azide hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Used as an azidation reagent to construct 1,2,3-triazole rings via copper-catalyzed azide–alkyne cycloaddition (CuAAC) | Reacted with terminal alkynes under inert atmosphere in the presence of a Cu(I) catalyst (e.g., CuSO₄/sodium ascorbate) at room temperature or elevated temperature to yield 1,4-disubstituted-1,2,3-triazole derivatives |
| Organic Synthesis | Imidazolesulfonyl-protected azide source offering tunable steric hindrance and improved stability over sodium azide | Under mild basic (e.g., Na₂CO₃) or neutral conditions, undergoes selective substitution or coupling with nucleophiles (e.g., amines, alcohols), followed by thermal or photolytic N₂ release to introduce a sulfonylimine moiety |
| Materials Science | Applied for end-group functionalization of polymers or surface modification to prepare triazole-containing stimuli-responsive materials | Covalently grafted onto alkyne-functionalized polymers, nanoparticles, or solid-phase supports via “click chemistry” to enable site-specific conjugation and modular assembly |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, condition (e.g., white to off-white crystalline powder), and presence of foreign matter with the naked eye. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Determine the infrared absorption spectrum of the sample and compare it with a standard spectrum to confirm characteristic functional groups (e.g., azido group —N₃, sulfonyl group, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Determine the hydrogen spectrum in deuterated solvent and compare the chemical shifts and integration area to verify molecular structure consistency. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 chromatographic column with a UV detector (typically 210–230 nm), and determine the main component content using external standard or area normalization method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Same as the content determination conditions or use a gradient elution program to separate and quantify potential impurities (e.g., unreacted raw materials, degradation products, etc.). |
| Azido Group Content | Titration (e.g., iodometric method) or elemental analysis | Quantify based on the reducing property of the azido group; or indirectly verify the presence and content of the azido group by determining the nitrogen content via elemental analysis. |
| Moisture | Karl Fischer Titration | Determine moisture content using volumetric or coulometric methods to ensure compliance with the requirement for loss on drying. |
| Residual Solvents | Gas Chromatography (GC) | Analyze by headspace or direct injection to detect organic solvents potentially remaining from synthesis or purification processes (e.g., dichloromethane, ethanol, etc.). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | Dry the sample at a specified temperature (e.g., 60–80°C) until constant weight is achieved, calculate the percentage of weight loss to assess volatile components and moisture. |
| Melting Point | Melting Point Apparatus | Determine the melting range using capillary or digital melting point apparatus as an auxiliary indicator of purity and identity. |
| pH Value (Solution) | pH Meter Measurement | Determine the pH value of a solution of a certain concentration to verify the hydrochloride salt form and acidity/basicity as expected. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline powder |
| Identification (1H-NMR) | Consistent with structure |
| Identification (LCMS) | Consistent with structure |
| Purity(HPLC) | ≥97% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.