China Factory Direct
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| CAS number | 953079-94-2 |
| Product name | PYRROLIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antiviral, antibacterial, or neurosystem-related drugs | Introduced into the target molecular scaffold via amidation, esterification, or condensation reactions |
| Organic Synthesis | Employed as a chiral building block in asymmetric synthesis reactions | Leverages its chiral center for stereoselective catalysis or stereoinduction |
| Pesticide Development | Applied in the synthesis of novel nitrogen-containing heterocyclic pesticide active ingredients | Condensed with halogenated hydrocarbons or sulfonyl chlorides to construct heterocyclic frameworks |
| Materials Science | Utilized as a functional monomer for preparing biocompatible polymeric materials | Incorporated into the polymer backbone via free-radical polymerization or ring-opening polymerization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Pyrrolidine-3-carboxylic acid hydrochloride content) | Acid-base titration with standardized NaOH solution | Quantifies the main component by neutralizing the hydrochloride salt with base and detecting the endpoint potentiometrically or using an indicator. |
| Water Content | Karl Fischer titration | Determines trace water based on stoichiometric reaction of iodine with water in a controlled anhydrous environment. |
| Residual Solvents (e.g., methanol, ethyl acetate) | Gas Chromatography (GC) with FID or MS detection | Separates and quantifies volatile organic solvents using capillary column chromatography and selective detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS or ICP-OES | Measures trace metal concentrations after acid digestion by detecting element-specific atomic emissions or mass-to-charge ratios. |
| Chloride Impurity | Ion Chromatography (IC) or potentiometric titration with AgNO₃ | Quantifies chloride ions via separation on an anion-exchange column or by argentometric titration. |
| Related Substances (impurities & degradation products) | Reverse-phase High-Performance Liquid Chromatography (RP-HPLC) with UV detection | Separates and quantifies structurally related impurities using C18 column and gradient elution, detected at 210–220 nm. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC with chiral stationary phase | Resolves enantiomers using a chiral column and quantifies enantiomeric excess based on peak area ratio. |
| pH (1% aqueous solution) | pH meter measurement | Measures hydrogen ion activity in a standardized aqueous solution using calibrated glass electrode. |
| Residue on Ignition (Sulfated Ash) | Gravimetric analysis after sulfuric acid treatment and high-temperature ignition | Determines inorganic residue content by igniting the sulfuric acid-treated sample and weighing the ash. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension by analyzing angular variation of scattered laser light. |
| Microbial Contamination | Membrane filtration followed by plate count (USP <61>) | Detects and enumerates aerobic microorganisms using filtration, membrane transfer to culture media, and colony enumeration. |
| Appearance (Color & Clarity) | Visual inspection against standard solutions (e.g., USP Color Standards) | Assesses physical appearance by comparing against reference standards under controlled lighting conditions. |
| Melting Point | Differential Scanning Calorimetry (DSC) or capillary melting point apparatus | Determines temperature range of solid-to-liquid transition by monitoring heat flow or visual observation of phase change. |
| Specific Optical Rotation | [α]D measurement using polarimeter | Measures degree of rotation of plane-polarized light induced by chiral molecules in solution at specified wavelength and concentration. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.