China Factory Direct
|
|
| CAS number | 955379-18-7 |
| Product name | N-tert-butyl-L-serineisopropyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D and Manufacturing | Synthetic intermediate for peptide-based and small-molecule drugs, used to construct bioactive compounds containing serine residues | Used as a protected serine derivative in solid-phase or solution-phase peptide synthesis; the Boc group protects the amino functionality, and the isopropyl ester protects the carboxyl functionality; selective deprotection and coupling are achieved via acidolysis (e.g., TFA) to remove the Boc group, followed by base-mediated or hydrogenolytic cleavage of the isopropyl ester |
| Organic Synthesis | Chiral building block for asymmetric synthesis and total synthesis of complex natural products | Employed as a chiral auxiliary or structural unit in transformations such as Diels–Alder reactions, alkylation, and amidation; the isopropyl ester enhances lipophilicity to facilitate extraction and purification, while the Boc group remains stable under diverse metal-catalyzed and reductive conditions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using UV detection at specified wavelength. |
| Related Substances | HPLC-UV | Separation and quantification of impurities based on retention time and UV response relative to main peak. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents using flame ionization detection after gas chromatographic separation. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent where water reacts stoichiometrically to determine moisture content. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of trace metal contaminants via inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residue by measuring atomic emission intensity after plasma excitation. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using polarimetry to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size based on angular scattering pattern of laser light passing through dispersed sample. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode and pH meter in aqueous suspension. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in methanol) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.