China Factory Direct
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| CAS number | 956100-62-2 |
| Product name | 4-Amino-8-bromo-2-chloroquinazoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate in the synthesis of anticancer agents (e.g., EGFR inhibitors) | Used to construct the quinazoline scaffold, with functional groups introduced via nucleophilic substitution, Suzuki coupling, and related reactions |
| Agrochemical R&D | Potential intermediate for pesticidal active molecules | Employed in heterocyclic compound synthesis to develop lead compounds for novel fungicides or insecticides |
| Chemical Research | Organic synthesis building block | Applied in the laboratory to synthesize polyhalogenated quinazoline derivatives, supporting structure–activity relationship (SAR) studies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient reverse-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents by gas chromatography with flame ionization detection against certified standards. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration based on iodine consumption in pyridine-methanol medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg, Ni) by mass spectrometric detection after acid digestion. |
| Chloride Content | Potentiometric Titration | Measures chloride ions using silver nitrate titrant with silver/silver chloride indicator electrode. |
| Bromide Content | Ion Chromatography | Separates and quantifies bromide anions using suppressed conductivity detection after ion exchange separation. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration under controlled white light. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles by analyzing angular scattering pattern of laser beam passing through dispersed sample. |
| Bulk Density | Tap Density Tester | Measures mass per unit volume of powder in a graduated cylinder after standardized mechanical tapping. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 248-252°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.