7-Aminocephalosporanic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 957-68-6 |
| Product name | 7-Aminocephalosporanic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7-Aminocephalosporanic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7-Aminocephalosporanic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7-Aminocephalosporanic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for synthesizing cephalosporin antibiotics | Prepared via chemical synthesis or microbial fermentation for manufacturing drugs such as cefixime and cefprozil |
| Biopharmaceuticals | Synthesis of antibiotic active pharmaceutical ingredients (APIs) | Serves as a key intermediate in multi-step chemical synthesis of various cephalosporin antibiotics |
| Chemical Synthesis | Production of cephalosporin drug precursors | Converted into diverse cephalosporin derivatives from 7-aminocephalosporanic acid through organic synthesis processes including acylation and cyclization |
Manufacturing Quality Control of 7-Aminocephalosporanic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | A reverse-phase chromatographic column is used with a phosphate buffer solution and an organic solvent as the mobile phase. The main peak area is detected using a UV detector (e.g., at 254 nm), and quantification is performed by external standard or internal standard method. |
| Related Substances (Impurities) | HPLC Method (Gradient Elution) | A gradient elution program is used to separate the main component from each impurity peak. Impurity content is assessed based on relative retention time and peak area ratio, meeting pharmacopoeia limit requirements. |
| Water Content | Karl Fischer Titration Method | The electrochemical titration principle is applied to accurately measure trace water content in the sample. This method is suitable for thermally unstable compounds such as 7-ACA. |
| Residual Solvents | Gas Chromatography (GC) | Headspace injection or direct injection is used with a capillary column to separate residual organic solvents (e.g., acetone, dichloromethane, etc.), and quantification is performed using an FID detector. |
| pH Value | pH Meter Method | The sample is prepared into a specified concentration aqueous solution, and its pH value is directly measured using a calibrated pH meter, ensuring it falls within the process or pharmacopoeia-specified range. |
| Optical Rotation | Polarimetry Method | At a specified wavelength (usually 589 nm) and temperature, the optical rotation of a solution of defined concentration is measured, and specific rotation is calculated for identification and purity control purposes. |
| Appearance | Visual Inspection Method | The physical characteristics of the sample, such as color, crystal form, and presence of foreign matter, are observed. It should be white or off-white crystalline powder. |
| Loss on Drying | Oven-Drying Weight Loss Method | The sample is dried at a specified temperature (e.g., 60°C under vacuum) until constant weight is achieved, and the percentage of mass loss is calculated to reflect volatile substances or adsorbed water content. |
| Heavy Metals | Thioglycolate Method / ICP-MS | The total amount of heavy metals such as lead, arsenic, and mercury is determined either by colorimetric methods (using thioglycolate reagent) or by Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to ensure safety. |
| Bacterial Endotoxins | Limulus Amebocyte Lysate (LAL) Assay | The LAL test utilizes limulus amebocyte lysate, which reacts with endotoxins through coagulation. Dynamic turbidimetry or endpoint chromogenic methods are used to determine endotoxin limits, ensuring the safety of injectable-grade raw materials. |
Technical Specifications of 7-Aminocephalosporanic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 175-179°C |
| Optical Rotation | +88.0 to +92.0° (c=1, in water) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7-Aminocephalosporanic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7-Aminocephalosporanic acid
Packaging of 7-Aminocephalosporanic acid
Industrial 7-Aminocephalosporanic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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