5-Bromo-2-fluoro-3-methylphenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 957120-61-5 |
| Product name | 5-Bromo-2-fluoro-3-methylphenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Bromo-2-fluoro-3-methylphenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Bromo-2-fluoro-3-methylphenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Bromo-2-fluoro-3-methylphenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serves as a synthetic intermediate for preparing bioactive drug molecules, including kinase inhibitors, anticancer agents, and anti-inflammatory compounds | Suzuki-Miyaura cross-coupling |
| Agrochemicals | Used to construct fluorinated aromatic scaffolds for novel pesticides or herbicides | Palladium-catalyzed cross-coupling |
| Materials Science | Serves as a building block for synthesizing fluorinated functional organic electronic materials (e.g., OLEDs, semiconductors) | Suzuki coupling polymerization or small-molecule coupling |
| Organic Synthesis | Enables modular construction of complex molecules by introducing the 5-bromo-2-fluoro-3-methylphenyl functional group | Transition metal-catalyzed C–C bond formation |
Manufacturing Quality Control of 5-Bromo-2-fluoro-3-methylphenylboronic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., residual starting materials, isomers, dehalogenated by-products) via gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, methanol) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Residual Palladium | ICP-OES | Measures palladium from Suzuki coupling catalyst residues via inductively coupled plasma optical emission spectroscopy after microwave-assisted digestion. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid impurities (if present) or acidic degradation products by titration with standardized NaOH solution using phenolphthalein indicator. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating purity and identity via comparison to literature value. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration under controlled white light against established reference. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in dry or suspended state using Mie scattering theory and calibrated optical model. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content (excluding water) by weight loss after heating at specified temperature (e.g., 105 C) under vacuum or nitrogen flow. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions (from hydrolysis or salt impurities) using suppressed conductivity detection after aqueous extraction and filtration. |
Technical Specifications of 5-Bromo-2-fluoro-3-methylphenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Bromo-2-fluoro-3-methylphenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Bromo-2-fluoro-3-methylphenylboronic acid
Safety Information of 5-Bromo-2-fluoro-3-methylphenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-Bromo-2-fluoro-3-methylphenylboronic acid
Industrial 5-Bromo-2-fluoro-3-methylphenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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