China Factory Direct
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| CAS number | 95753-55-2 |
| Product name | Fmoc-4-nitro-L-phenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Monomer for synthesizing peptides and proteins | Solid-phase or solution-phase synthesis using Fmoc protection |
| Biotechnology | Preparation of labeled peptide segments | Nitro group employed as a spectroscopic probe |
| Pharmaceutical R&D | Probe molecules for drug screening | Amino acid building blocks in peptide synthesis |
| Analytical Chemistry | Synthesis of standard peptides for mass spectrometry analysis | Solid-phase synthesis or stepwise coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorbance at 268 nm using reverse-phase C18 column and gradient elution with aqueous/organic mobile phase. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., Fmoc-Phe-OH, nitrophenylalanine, di-Fmoc derivatives) using validated HPLC method. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in pyridine/methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of Pd catalyst residues from synthesis using ICP-MS with isotope dilution or external calibration. |
| Chloride Ion | Ion Chromatography | Separates and quantifies chloride anion using suppressed conductivity detection after anion-exchange column separation. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under controlled temperature and vacuum for specified time. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using Mie scattering theory and laser diffraction analysis. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | -43 to -37° (c=1, DMF) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.