Disulfiram Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 97-77-8 |
| Product name | Disulfiram |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Disulfiram
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Disulfiram Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Disulfiram
| Industry | Application | Process |
|---|---|---|
| Rubber Industry | Vulcanization accelerator | Used in the vulcanization of natural and synthetic rubber to accelerate crosslinking reactions and improve vulcanization efficiency |
| Rubber Industry | Scorch inhibitor (delay agent) | Suppresses premature vulcanization during mixing and processing to enhance processing safety |
| Rubber Industry | Sulfur donor | Provides reactive sulfur atoms for crosslinking in sulfur-free or low-sulfur formulations |
| Polymer Industry | Free-radical initiator | Initiates monomer polymerization in emulsion or solution polymerization systems |
| Pesticide Industry | Fungicide intermediate | Serves as a raw material for synthesizing certain sulfur-containing fungicides or insecticides |
| Analytical Chemistry | Colorimetric reagent | Used for colorimetric determination of metal ions such as copper and silver |
| Pharmaceutical Industry | Antiparasitic drug intermediate | Acts as a precursor compound in the synthesis of anthelmintic or antifungal drugs |
Manufacturing Quality Control of Disulfiram
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Assay (Purity) | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with methanol/water or acetonitrile/water as the mobile phase. The TETD peak area is detected by a UV detector (typically at 254 nm), and the assay is calculated using external or internal standard methods. Offers high accuracy and good reproducibility. |
| Gas Chromatography (GC) | Suitable for volatile samples, which may require derivatization. Separation is achieved using a capillary column, with quantification by FID detection. Applicable for residual organic solvents and main component analysis, but caution is needed for thermally unstable substances. | |
| Melting Point | Melting Point Apparatus Method | Determined according to Chinese Pharmacopoeia or ASTM standards using capillary method or automatic melting point apparatus. The theoretical melting point of TETD is 130–135°C, used for preliminary assessment of purity and crystalline form consistency. |
| Moisture Content | Karl Fischer Titration | Based on the quantitative reaction of iodine-sulfur dioxide-pyridine-methanol system with water. Moisture content is determined by potentiometric or coulometric methods. Essential for controlling moisture that affects storage stability (TETD is hygroscopic). |
| Residue on Ignition (Ash Content) | Ignition and Gravimetric Method | The sample is ignited at high temperature (500–600°C) until constant weight. The residue is weighed to calculate ash content, used to evaluate levels of inorganic impurities (e.g., metal catalyst residues). |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion of the sample, AAS or ICP-MS is used to determine concentrations of heavy metals such as lead, cadmium, mercury, and arsenic. Ensures compliance with pharmaceutical or food-grade rubber additive standards (e.g., FDA, REACH). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Using headspace sampling technique to detect residual organic solvents (e.g., ethanol, acetone, toluene) from manufacturing processes. Controlled against limits specified in ICH Q3C guidelines to ensure product safety. |
| Chloride Content | Ion Chromatography (IC) or Silver Nitrate Titration | After dissolving the sample, chloride ion concentration is measured by ion chromatography, or by titration with silver nitrate standard solution forming AgCl precipitate, with endpoint detection by indicator. Used to control chloride impurities in raw materials. |
| Sulfur Content | Combustion-Iodometric Method or Sulfur Analyzer | The sample is combusted at high temperature, converting sulfur to SO₂, which is absorbed and titrated with iodine solution, or directly measured using a dedicated sulfur analyzer. Assesses whether sulfur content matches the theoretical value based on molecular formula (C₈H₁₆N₂S₄). |
| Appearance and Color | Visual Comparison or Colorimeter | Sample should appear as white to light yellow crystalline powder, free from visible impurities. A colorimeter (e.g., HunterLab) may be used to quantify yellowness index (YI), ensuring color consistency between batches. |
| Solubility and pH (aqueous suspension) | Solubility Test + pH Meter | Sample is suspended in water to observe solubility (TETD is nearly insoluble in water); the supernatant is tested for pH (should be near neutral, pH 6–8), indicating possible acidic/alkaline impurity contamination. |
| Thermal Stability (DSC/TGA) | Differential Scanning Calorimetry (DSC) / Thermogravimetric Analysis (TGA) | DSC detects melting endothermic peaks and decomposition temperatures; TGA monitors weight loss curves to assess onset of thermal decomposition (typically >200°C). Used for process control and evaluation of storage conditions. |
Technical Specifications of Disulfiram
| Test Item | Specification |
|---|---|
| Appearance | White to orange to green crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 135–142°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Disulfiram
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Disulfiram
Packaging of Disulfiram
Industrial Disulfiram Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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