16,17-Epoxypregnenolone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 974-23-2 |
| Product name | 16,17-Epoxypregnenolone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 16,17-Epoxypregnenolone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 16,17-Epoxypregnenolone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 16,17-Epoxypregnenolone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of glucocorticoids and progestins | Prepared via selective epoxidation of pregnenolone; widely employed in multi-step synthetic routes to steroidal hormones such as betamethasone and dexamethasone |
| Pharmaceutical R&D | Used in structure–activity relationship (SAR) studies and lead optimization of novel steroidal drugs | Serves as a scaffold for bioactive molecules; novel anti-inflammatory or contraceptive drug candidates are generated through functional group modifications (e.g., hydroxylation, halogenation, esterification) |
| Chemical Synthesis | Highly selective steroidal epoxide intermediate for total synthesis of complex natural products | Functions as a chiral template in multi-step organic synthesis; complex steroidal frameworks are constructed via stereoselective ring-opening or rearrangement reactions |
Manufacturing Quality Control of 16,17-Epoxypregnenolone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 240-254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification relies on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion by inductively coupled plasma mass spectrometry with isotopic detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion with sulfuric acid treatment and high-temperature incineration to constant weight. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light (589 nm) in solution to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition using calibrated capillary tube method per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size via Mie scattering theory using dispersed aerosol in air stream. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to soybean-casein digest agar, and incubation per USP <61>. |
| Residual Catalyst (Pd) | ICP-OES | Quantifies palladium residues after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
Technical Specifications of 16,17-Epoxypregnenolone
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 172–176°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -45° to -55° (c=1, in chloroform) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 16,17-Epoxypregnenolone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 16,17-Epoxypregnenolone
Industrial 16,17-Epoxypregnenolone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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