4-Methoxybenzenesulfonyl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 98-68-0 |
| Product name | 4-Methoxybenzenesulfonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methoxybenzenesulfonyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methoxybenzenesulfonyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methoxybenzenesulfonyl chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antiplatelet drug ticagrelor | Prepared via multi-step reactions—including sulfonylation and cyclization—with 3-(2-chloroethyl)-1H-indol-5-ol |
| Pesticides | Intermediate in the synthesis of the insecticide pymetrozine | Used to construct the pyridone ring structure; the sulfonyl group is introduced via nucleophilic substitution and condensation reactions |
| Dyes | Modifying agent for azo components in reactive dyes | Serves as a sulfonyl chloride protecting group for diazo components; removed by hydrolysis after coupling to fine-tune dyeing performance |
| Organic Synthesis | Sulfonylation reagent for hydroxyl/amino group protection | Reacts with alcohols or amines under anhydrous conditions to form p-methoxybenzenesulfonate esters or sulfonamides, enabling selective protection |
Manufacturing Quality Control of 4-Methoxybenzenesulfonyl chloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration measuring water content via reaction of iodine with sulfur dioxide in the presence of water and base. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities (e.g., residual sulfonic acid) using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of non-volatile inorganic residue after controlled high-temperature ashing and weighing. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals by atomization in flame or graphite furnace and measurement of characteristic absorption wavelength. |
| Chloride Impurity | Potentiometric Titration with AgNO3 | Precipitation titration using silver nitrate, with endpoint detected by silver ion-selective electrode. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reversed-phase column and UV absorbance at 254 nm. |
| Melting Point | Capillary Melting Point Determination | Thermal transition observed as the temperature range over which solid transforms to liquid under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Solubility in Common Solvents | Qualitative Solubility Test | Observation of complete dissolution in specified solvents (e.g., chloroform, acetone) at room temperature. |
| Sulfate Ash | Gravimetric Analysis (Sulfated Ash Method) | Conversion of organic matter to sulfate salts followed by ignition and gravimetric determination of residual inorganic sulfate. |
| Volatile Impurities | Headspace Gas Chromatography (HS-GC) | Detection and quantification of low-boiling impurities (e.g., solvents, chlorinated by-products) via equilibrium headspace sampling and GC analysis. |
Technical Specifications of 4-Methoxybenzenesulfonyl chloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (by GC) |
| Melting Point | 48–52°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methoxybenzenesulfonyl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methoxybenzenesulfonyl chloride
Safety Information of 4-Methoxybenzenesulfonyl chloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-Methoxybenzenesulfonyl chloride
Industrial 4-Methoxybenzenesulfonyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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