2-Picolinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 98-98-6 |
| Product name | 2-Picolinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Picolinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Picolinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Picolinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used as a ligand or precursor in the preparation of active pharmaceutical ingredients (APIs), including antitumor and antimicrobial agents |
| Agrochemicals | Agrochemical intermediates | Applied in the synthesis of nitrogen-containing heterocyclic agrochemicals for insecticides and herbicides |
| Coordination Chemistry | Synthesis of metal complexes | Employed as a chelating ligand to form stable complexes with transition metals (e.g., copper, zinc, cobalt) for catalysis or materials research |
| Materials Science | Preparation of functional materials | Utilized in the synthesis of organic–inorganic hybrid materials exhibiting functionalities such as fluorescence or magnetism |
| Organic Synthesis | Reagent in organic reactions | Applied as a building block in coupling, esterification, amidation, and other reactions to synthesize complex organic molecules |
Manufacturing Quality Control of 2-Picolinic acid
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Examine the color and physical state of the sample under natural or standard lighting to determine if it is a white to off-white crystalline powder, and check for impurities, caking, or other abnormalities. |
| Identification | Infrared Spectroscopy (IR) | Prepare a pellet with potassium bromide and measure the infrared absorption spectrum. Compare with reference spectrum to confirm consistency of characteristic functional group peaks (e.g., carboxyl, pyridine ring). |
| Proton Nuclear Magnetic Resonance (¹H-NMR) | Dissolve the sample in a deuterated solvent (e.g., DMSO-d₆) and record the ¹H-NMR spectrum. Confirm molecular structure by analyzing characteristic chemical shifts (e.g., pyridine ring protons, protons adjacent to carboxyl group). | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with water-methanol or buffer solution as mobile phase. Detect at approximately 260 nm using a UV detector. Quantify active ingredient by external or internal standard method. |
| Acid-Base Titration | Exploit the acidic nature of 2-pyridinecarboxylic acid by titrating with standardized NaOH solution. Use phenolphthalein or potentiometric detection to determine endpoint and calculate purity. Suitable for rapid assay of high-purity active pharmaceutical ingredients. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate main peak from impurity peaks using gradient or isocratic elution. Detection limit typically reaches 0.05%–0.1%. Used to evaluate organic impurities such as synthesis by-products and degradation products. |
| Water Content | Karl Fischer Titration | Determine moisture content using coulometric or volumetric Karl Fischer method. Suitable for trace moisture analysis to ensure product stability. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Method | Dry the sample at specified temperature (e.g., 105°C) to constant weight and calculate percentage weight loss to assess volatile components or residual solvents. |
| Sulfated Ash | Sulfated Ash Residue Method | Char the sample at high temperature, treat with sulfuric acid, then incinerate at 700–800°C to constant weight. Weigh the residue to estimate inorganic impurity content. |
| Heavy Metals | Sulfide Colorimetry or ICP-MS | Follow pharmacopoeial methods (e.g., ChP or USP) to determine total heavy metals (e.g., lead, cadmium, mercury) either by colorimetric reaction with sodium sulfide or by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, use headspace sampling with gas chromatography to detect organic solvents possibly remaining from manufacturing processes (e.g., methanol, ethanol, acetone). |
Technical Specifications of 2-Picolinic acid
| Test Item | Specification |
|---|---|
| Appearance | White to Almost white powder to crystal |
| Purity | ≥99.0% |
| Loss on drying | ≤0.5% |
| Water | ≤0.5% |
| Sulfate | ≤0.1% |
| Heavy metals | ≤20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Picolinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Picolinic acid
Packaging of 2-Picolinic acid
Industrial 2-Picolinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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