China Factory Direct
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| CAS number | 98600-34-1 |
| Product name | 4-Bromoindole-3-carboxaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate for constructing active pharmaceutical ingredients (APIs) containing indole scaffolds, such as kinase inhibitors and antitumor compounds | Used in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) or as an aldehyde group in functional group transformations including reductive amination and Wittig reactions |
| Agrochemical R&D | Key intermediate for structural modification of novel insecticidal and fungicidal molecules | Applied in nucleophilic substitution or metal-catalyzed coupling via the bromine atom to introduce heterocyclic or aryl side chains for optimizing biological activity |
| Materials Science | Building block for organic optoelectronic functional materials, such as OLED emissive layers or hole-transport layers | The bromine atom is used in Ullmann or Buchwald-Hartwig coupling to link charge-transporting moieties (e.g., carbazole, triphenylamine); the aldehyde group is employed in Schiff base condensation to prepare conjugated ligands |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 280 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by retention time and UV response relative to the main peak. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., DMF, dichloromethane) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine consumption in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni) after acid digestion by detecting elemental mass-to-charge ratios with high sensitivity. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Quantifies palladium from catalytic hydrogenation residues by plasma excitation and emission intensity measurement at characteristic wavelengths. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation of phase change. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard reference samples. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under specified temperature and vacuum conditions to determine volatile content. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral centers in solution using sodium D-line illumination. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a defined suspension in water using calibrated glass electrode and standardized buffer calibration. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (by NMR) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148-152°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.