DMT-dT Phosphoramidite Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 98796-51-1 |
| Product name | DMT-dT Phosphoramidite |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for DMT-dT Phosphoramidite
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk DMT-dT Phosphoramidite Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of DMT-dT Phosphoramidite
| Industry | Application | Process |
|---|---|---|
| Biotechnology | Oligonucleotide synthesis reagent | Used in solid-phase phosphoramidite synthesis of DNA fragments, serving as a protected form of 3′-deoxythymidine for sequence assembly |
| Pharmaceutical R&D | Nucleic acid-based drug intermediate | Employed as a modified nucleoside building block in the synthesis of antisense oligonucleotides, siRNA, and other therapeutic molecules |
| Molecular diagnostics | Probe preparation | Provides specific base modifications to enhance stability or specificity during synthesis of fluorescently labeled or unlabeled nucleic acid probes |
Manufacturing Quality Control of DMT-dT Phosphoramidite
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 260 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents per ICH Q3C. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine-based reagent to determine trace water content. |
| Optical Rotation | [alpha]D Measurement | Polarimetric measurement at 20 C using sodium D-line to confirm chiral integrity and identity. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to quantify acidic impurities. |
| Phosphorus Content | ICP-OES | Quantification of total phosphorus after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Heavy Metals | ICP-MS | Multi-element detection of Pb, Cd, Hg, As, and Ni after microwave digestion, per ICH Q3D. |
| Residual Cyanide | Ion Chromatography | Separation and quantification of free cyanide ions using suppressed conductivity detection. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry powder particle size distribution via laser scattering in air dispersion mode. |
| Bulk Density | Weight/Volume Method | Determination of mass per unit volume after controlled tapping in a calibrated cylinder. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer, and incubation on TSA agar. |
Technical Specifications of DMT-dT Phosphoramidite
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +15.0 to +17.0° (c=1, CHCl3) |
| Melting Point | 118 to 122°C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of DMT-dT Phosphoramidite
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of DMT-dT Phosphoramidite
Packaging of DMT-dT Phosphoramidite
Industrial DMT-dT Phosphoramidite Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply