N-Boc-3-carboethoxy-4-piperidone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 98977-34-5 |
| Product name | N-Boc-3-carboethoxy-4-piperidone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Boc-3-carboethoxy-4-piperidone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Boc-3-carboethoxy-4-piperidone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Boc-3-carboethoxy-4-piperidone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of piperidine-containing drug molecules, such as antidepressants and antipsychotics | Applied as a Boc-protected piperidinone carboxylate ester, participating in condensation, reduction, or cyclization reactions during multistep organic synthesis |
| Organic Synthesis | Serves as a key building block for constructing complex nitrogen-containing heterocycles | Applied in deprotection, functional group transformation, or reaction with nucleophiles to introduce target substituents |
| Drug Discovery | Used for lead compound optimization in high-throughput screening or structure–activity relationship (SAR) studies | Applied as a core scaffold for structural modification in combinatorial or parallel synthesis |
Manufacturing Quality Control of N-Boc-3-carboethoxy-4-piperidone
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state (e.g., white to off-white powder), presence of lumps, or visible impurities. |
| Identification (Structural Confirmation) | Nuclear Magnetic Resonance Spectroscopy (¹H NMR, ¹³C NMR) | Analyze characteristic peaks in proton and carbon spectra to confirm structural features such as Boc protecting group, ester group, carbonyl group, and the piperidine ring. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Detect characteristic functional group absorption peaks, such as C=O (~1700–1750 cm⁻¹), C-O (ester, ~1200 cm⁻¹), N-H (no free NH in Boc), etc. | |
| Mass Spectrometry (MS or HRMS) | Determine molecular ion peaks [M+H]⁺ or [M+Na]⁺ to verify molecular weight and confirm the molecular formula of the target compound. | |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column and UV detector (typically set at 210–254 nm), determine purity by area normalization or external standard method. |
| Impurity Analysis | HPLC-DAD / LC-MS | Combine HPLC with diode array detection or mass spectrometry to identify and quantify organic impurities (e.g., de-Boc product, hydrolysis products, isomers, etc.). |
| Water Content | Karl Fischer Titration | Accurately measure water content in the sample, suitable for moisture-sensitive intermediates or where loss on drying needs to be controlled. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents potentially residual from the manufacturing process (e.g., methanol, ethanol, ethyl acetate, dichloromethane, etc.) according to ICH guidelines. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the compound, used for preliminary assessment of purity and consistency (if it is a crystalline solid). |
| Loss on Drying (LOD) | Thermogravimetric Analysis (TGA) or Oven Method | Heat the sample at a specified temperature for a defined time and measure the weight loss to assess volatile components (including moisture and solvents). |
| Sulfated Ash (Residue on Ignition) | Gravimetric Method | Treat the sample with sulfuric acid, then ignite at high temperature, and weigh the remaining inorganic residue to assess inorganic impurity content. |
| Boc Protecting Group Content (Optional) | Quantitative NMR (qNMR) | Use an internal standard method (e.g., 1,3,5-trimethoxybenzene) for absolute quantification to determine the proportion of Boc groups and verify substitution degree. |
Technical Specifications of N-Boc-3-carboethoxy-4-piperidone
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 75–79 °C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0 to -19.0 ° (c=1, CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Boc-3-carboethoxy-4-piperidone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Boc-3-carboethoxy-4-piperidone
Safety Information of N-Boc-3-carboethoxy-4-piperidone
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-Boc-3-carboethoxy-4-piperidone
Industrial N-Boc-3-carboethoxy-4-piperidone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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