1-Boc-3-piperidone Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 98977-36-7 |
| Product name | 1-Boc-3-piperidone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 1-Boc-3-piperidone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Boc-3-piperidone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Boc-3-piperidone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for synthesizing active pharmaceutical ingredients (APIs) containing a piperidine ring (e.g., NK1 receptor antagonists, β-secretase inhibitors) | Used as a protected piperidinone building block in multistep total synthesis; employed in reduction, amination, and Boc deprotection to construct the target molecular scaffold |
| Organic Synthesis | Precursor to chiral piperidine derivatives for preparing optically pure pharmaceutical intermediates | Applied in asymmetric reduction or α-functionalization with chiral reagents or catalysts, followed by selective Boc deprotection |
| Agrochemical R&D | Building block for nitrogen-containing heterocyclic structures in novel insecticides/fungicides | Participates in cycloaddition or nucleophilic substitution reactions to introduce functionalized piperidine rings, optimizing target binding affinity and metabolic stability of agrochemical molecules |
Manufacturing Quality Control of 1-Boc-3-piperidone
| Test Item | Common Test Method | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (e.g., white to off-white crystalline or powder) to determine if it meets the standard description. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a C18 reversed-phase column with an appropriate mobile phase (e.g., acetonitrile/water or methanol/buffer salt) under gradient or isocratic elution. Detect with a UV detector (e.g., 210–220 nm) and calculate the purity percentage based on the main peak area. |
| Related Substances / Impurities | HPLC (Related Substances Analysis) | Under the same conditions as the purity test, integrate impurity peaks before and after the main peak. Calculate individual and total impurity levels using area normalization or external standard method, ensuring compliance with specified limits (e.g., individual impurity ≤0.5%, total impurities ≤1.0%). |
| Water Content | Karl Fischer Moisture Determination | Use volumetric or coulometric method. Dissolve the sample in a suitable solvent (e.g., methanol), titrate to the endpoint, and calculate the water content (typically required ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Analyze using headspace or direct injection, with a DB-624 or similar capillary column and FID detector to quantify residual organic solvents (e.g., ethyl acetate, toluene, dichloromethane), in compliance with ICH Q3C limits. |
| Melting Point | Capillary Melting Point Determination | Use a digital melting point apparatus. Place a small amount of sample in a capillary tube and heat at a controlled rate (e.g., 1–2°C/min). Record the initial and final melting temperatures and confirm if within the standard range (e.g., ±2°C from literature value). |
| Optical Rotation (if applicable) | Polarimetry | If the compound is chiral or optical purity needs to be controlled, prepare a solution of defined concentration and measure specific optical rotation at a specified wavelength (e.g., 589 nm). |
| Structure Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | NMR (¹H & ¹³C) confirms hydrogen and carbon framework and substituents; IR verifies characteristic functional groups (e.g., Boc carbonyl ~1700 cm⁻¹); MS confirms molecular ion peak (m/z = 213 [M+H]⁺). |
| pH Value (if solution or acid/base control required) | pH Meter Measurement | Prepare a solution or suspension of defined concentration, calibrate the pH meter, and measure the pH to assess acid-base stability or residual acid/base catalysts. |
| Residue on Ignition / Ash Content | Gravimetric Method | Iignite the sample in a muffle furnace at high temperature (e.g., 600–800°C) until constant weight, cool and weigh the residue, then calculate the ash content percentage (typically required ≤0.1%). |
Technical Specifications of 1-Boc-3-piperidone
| Test Item | Specification |
|---|---|
| Appearance | White to light orange crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 1-Boc-3-piperidone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Boc-3-piperidone
Packaging of 1-Boc-3-piperidone
Industrial 1-Boc-3-piperidone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply