China Factory Direct
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| CAS number | 100-06-1 |
| Product name | 4'-Methoxyacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Fragrance Industry | Used as a fixative and intermediate in fragrance synthesis, imparting floral notes such as jasmine and lily-of-the-valley | Friedel–Crafts acylation with acetyl chloride or acetic anhydride under Lewis acid catalysis (e.g., AlCl₃), or multi-step synthesis involving decarboxylation/esterification–reduction–oxidation of p-methoxyphenylacetic acid |
| Pharmaceutical Industry | Key intermediate in the synthesis of antiarrhythmic propafenone and antidepressant trazodone | Bromination, cyanation, and hydrolysis to yield p-methoxyphenylpyruvic acid, followed by condensation, cyclization, and amination to construct the target molecular scaffold |
| Agrochemical Industry | Structural unit for synthesizing novel phenoxy carboxylic acid herbicides and plant growth regulators | Participates in coupling reactions (e.g., Suzuki, Heck) as an aryl substituent; the methoxyacetyl side chain is introduced to optimize biological activity |
| Organic Synthesis | General aromatic ketone building block for preparing chalcones, flavones, benzodihydropyrans, and other heterocyclic compounds | C=C, C–N, or C–O bond formation via aldol condensation, Wittig reaction, reductive amination, or transition metal-catalyzed C–H activation |
| Detection Item | Common Detection Method | Method Overview |
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| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase column with methanol/water or acetonitrile/water as the mobile phase, and a UV detector (e.g., 254 nm) for quantitative analysis of the main component's purity. Suitable for high-precision quantification. |
| Content Determination | Gas Chromatography (GC) | Utilizes a capillary column for separation and a Flame Ionization Detector (FID) for quantification. Suitable for volatile organic compounds; requires the sample to be vaporizable and thermally stable. |
| Impurity Analysis | HPLC-UV / GC-MS | HPLC combined with UV detection is used for known impurities; GC-MS or LC-MS is used for structural identification and semi-quantitative analysis of unknown impurities. |
| Moisture Content | Karl Fischer Titration | Determines trace moisture in the sample using coulometric or volumetric methods. Suitable for moisture-sensitive organic compounds in quality control. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Determines the temperature at which a substance transitions from solid to liquid, serving as a physical constant to verify compound identity and provide an initial estimate of purity. |
| Residual Solvent | Headspace Gas Chromatography (HS-GC) | After sealing and heating the sample, the headspace gas is injected into GC-FID or GC-MS for quantitative analysis of residual organic solvents (e.g., methanol, ethyl acetate, etc.). |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, the total content of elements such as lead, arsenic, cadmium, and mercury is determined to ensure compliance with pharmacopoeia or industry safety standards. |
| Appearance and Color | Visual Color Comparison / Colorimeter | Determines the color of the sample solution or solid by comparing it to standard color solutions or using a colorimeter to check whether it meets the appearance requirements specified in quality standards. |
| pH Value (if it is a solution formulation) | pH Meter Measurement | Used to measure the acidity or alkalinity after dissolution, ensuring it remains within a stable range to avoid affecting subsequent use or stability. |
| Test Item | Specification |
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| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 47.0–49.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.