China Factory Direct
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| CAS number | 100-09-4 |
| Product name | 4-Methoxybenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for certain antibiotics and anti-inflammatory drugs | Used to convert p-hydroxybenzoic acid to p-anisic acid via methylation |
| Fine Fragrances | Raw material for fragrance synthesis, applied in floral fragrance formulations | Applied in the synthesis of aromatic compounds via methoxylation |
| Personal Care & Cosmetics | Fragrance additive for perfumes and skincare products | Incorporated as a fragrance component into cosmetic formulations |
| Pesticides | Synthesis of pesticide intermediates for certain herbicides and insecticides | Combined with other compounds via esterification or amidation to form active pesticide ingredients |
| Test Item | Common Testing Method | Method Overview |
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| Appearance and Properties | Visual Inspection + Melting Point Determination | Observe sample color, crystal form, and presence of impurities; use a melting point apparatus to determine the melting point (literature value approx. 167–170°C) to assess purity. |
| Purity Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a C18 chromatographic column with methanol-water (or buffer salt) as the mobile phase, and detect using a UV detector (230–254 nm). Quantify using external standard method, and simultaneously detect impurities. |
| Purity Content Determination | Gas Chromatography (GC) | Suitable for volatile derivatives (e.g., after methyl esterification), use a capillary column for separation and FID detection. Applicable for quantifying organic solvent residues and main components. |
| Purity Content Determination | Acid-Base Titration Method | Determine carboxyl group content by titrating sample aqueous solution with sodium hydroxide standard solution (phenolphthalein indicator). Suitable for rapid rough assessment of purity. |
| Water Content Determination | Karl Fischer Titration | Accurately measure trace water in samples, suitable for moisture-sensitive raw materials or high-purity requirements. |
| Melting Point | Capillary Melting Point Apparatus or Automatic Melting Point Apparatus | Determine the melting point range of pure compounds (167–170°C). A wide or lower melting range indicates impurities, serving as a basic purity indicator. |
| Impurity Detection (Organic Impurities) | HPLC Method (Impurity Spectrum Analysis) | Use gradient elution to detect possible impurities such as o-/m-methoxybenzoic acid, unreacted p-methoxytoluene, and oxidation products. The quantitation limit is usually ≤0.1%. |
| Heavy Metal Detection | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine heavy metal content (e.g., lead, cadmium, mercury, arsenic) after sample ashing or digestion, meeting pharmacopoeia limits (e.g., ≤10 ppm). |
| Sulfate Ash | Residue on Ignition Method | Measure the weight of residue after high-temperature ashing to evaluate inorganic impurity content, typically required to be ≤0.1%. |
| Solvent Residues | Gas Chromatography (GC-MS or GC-FID) | Detect residual organic solvents from the production process, such as methanol, ethanol, ethyl acetate, according to ICH Q3C limit criteria. |
| Crystal Form Analysis (Optional) | X-ray Powder Diffraction (XRPD) | Used to confirm crystal structure and crystalline consistency, applicable for high-end APIs requiring specific crystal forms. |
| UV-Visible Absorption Spectrum | UV-Vis Spectrophotometry | Determine characteristic absorption peaks (λmax ≈230–240 nm) in ethanol or methanol for qualitative identification and rapid concentration estimation. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 182-186°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 340-355 mg KOH/g |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.