4-Nitroacetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 100-19-6 |
| Product name | 4-Nitroacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Nitroacetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Nitroacetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Nitroacetophenone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibiotics (e.g., chloramphenicol) and antimalarial drug intermediates | Nitration, Friedel-Crafts acylation |
| Dyes | Intermediate for dye synthesis, including azo dyes and other colorants | Diazotization, coupling reactions |
| Pesticides | Intermediate for insecticide and herbicide synthesis | Reduction, condensation |
| Organic Synthesis | Preparation of other nitroaromatic compounds and fine chemicals | Catalytic hydrogenation, oxidation |
| Research | Analytical reagent or reference standard for organic synthesis research | Purification (e.g., crystallization, distillation) |
Manufacturing Quality Control of 4-Nitroacetophenone
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase chromatography column with mobile phases such as methanol-water or acetonitrile-water, and a UV detector (e.g., at 254 nm) for quantitative analysis of the main component's purity. Suitable for accurately determining the content of p-nitroacetophenone and its impurity profile. |
| Impurity Content | HPLC or GC-MS | Separates individual components via HPLC, or identifies the structure and content of volatile impurities using gas chromatography-mass spectrometry (GC-MS) to evaluate product purity and residual by-products. |
| Melting Point Determination | Capillary Melting Point Apparatus | According to pharmacopoeial or standard methods, measures the melting temperature range of the sample (literature value: approximately 80–83°C) to assess purity and crystalline form consistency. |
| Water Content | Karl Fischer Titration | Relies on the quantitative reaction between water, iodine, and sulfur dioxide in a pyridine/methanol system to precisely determine trace moisture content, preventing adverse effects on stability or reactivity. |
| Appearance and Color | Visual Color Comparison | Observes the solid color (typically pale yellow crystals) under natural or standard lighting and compares it with a standard color chart or reference sample to assess abnormal discoloration. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Heats the sample to release residual organic solvents, which are then quantified using GC-FID or GC-MS to ensure compliance with ICH Q3C limits for solvent residues. |
| Structural Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR), Nuclear Magnetic Resonance (NMR) | FT-IR compares characteristic functional group absorption peaks (e.g., carbonyl, nitro groups); ¹H/¹³C NMR confirms molecular structure and substitution positions for raw material identification and batch consistency verification. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, detects heavy metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with safety standards for pharmaceutical or industrial-grade raw materials. |
| Drying Loss | Drying to Constant Weight | Dries the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, then calculates the percentage of mass loss to reflect volatile substances or adsorbed water content. |
Technical Specifications of 4-Nitroacetophenone
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to brown crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 77.0–79.5°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Nitroacetophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Nitroacetophenone
Packaging of 4-Nitroacetophenone
Industrial 4-Nitroacetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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