1-bromo-2-chloro-3-fluoro-4-iodobenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1000573-03-4 |
| Product name | 1-bromo-2-chloro-3-fluoro-4-iodobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-bromo-2-chloro-3-fluoro-4-iodobenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-bromo-2-chloro-3-fluoro-4-iodobenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-bromo-2-chloro-3-fluoro-4-iodobenzene
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate for constructing active pharmaceutical ingredients (APIs) containing polyhalogenated aromatic rings | Applied in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck reactions) |
| Materials Science | Structural unit for liquid crystal monomers or organic optoelectronic materials | Applied in nucleophilic substitution or metal-catalyzed C–X bond transformation reactions |
| Agrochemical R&D | Lead compound modification for novel agrochemicals | Applied in halogen exchange reactions or as a multifunctionalized aromatic ring scaffold |
Manufacturing Quality Control of 1-bromo-2-chloro-3-fluoro-4-iodobenzene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID or MS detection | Quantifies the main component by separation on a capillary column and detection via flame ionization or mass spectrometry, using external calibration with certified reference standard. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatiles are equilibrated in headspace vial and analyzed by GC-FID to quantify common solvents (e.g., acetone, dichloromethane, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water; measures trace moisture content in organic matrix. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Sample digested in acid matrix; elements quantified based on isotope-specific mass-to-charge ratios with ultra-trace sensitivity and multi-element capability. |
| Chloride Impurity (e.g., Cl⁻ from hydrolysis) | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on ion-exchange column; chloride quantified by conductivity response relative to calibration standards. |
| Acidic/Basic Impurities | Acid-Base Potentiometric Titration | Titration with standardized NaOH or HCl solution monitored by pH electrode; determines total titratable acidic or basic species arising from degradation or synthesis by-products. |
| Residual Catalysts (e.g., Pd, Cu) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Acid-digested sample analyzed for catalytic metal residues via element-specific atomic emission lines at characteristic wavelengths. |
| Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral impurities or enantiomeric excess; confirms absence of significant chiral contamination (though compound is achiral, method verifies structural integrity). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change; deviation from literature value (72–74 °C) indicates impurity or polymorphic inconsistency. |
| Spectral Identity | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirms molecular structure via characteristic absorption bands (e.g., C–Br, C–Cl, C–F, C–I stretches) matched against reference spectrum. |
| Nuclear Magnetic Resonance (¹H & ¹³C NMR) | Nuclear Magnetic Resonance Spectroscopy | Verifies substitution pattern and molecular connectivity through chemical shift, integration, and coupling patterns in deuterated solvent. |
| Non-Volatile Residue (NVR) | Gravimetric Analysis (Evaporation & Weighing) | Sample evaporated to dryness under controlled conditions; residue weighed to assess inorganic/organic non-volatiles per USP <461>. |
Technical Specifications of 1-bromo-2-chloro-3-fluoro-4-iodobenzene
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-bromo-2-chloro-3-fluoro-4-iodobenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-bromo-2-chloro-3-fluoro-4-iodobenzene
Safety Information of 1-bromo-2-chloro-3-fluoro-4-iodobenzene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-bromo-2-chloro-3-fluoro-4-iodobenzene
Industrial 1-bromo-2-chloro-3-fluoro-4-iodobenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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