Methyl 3-amino-5-phenylthiophene-2-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 100063-22-7 |
| Product name | Methyl 3-amino-5-phenylthiophene-2-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 3-amino-5-phenylthiophene-2-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 3-amino-5-phenylthiophene-2-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 3-amino-5-phenylthiophene-2-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate for constructing drug molecules containing a thiophene ring | Prepared via multi-step organic synthesis, including substitution and esterification reactions on the thiophene ring; commonly used to construct biologically active heterocyclic compounds |
| Pharmaceutical Manufacturing | Precursor for synthesizing anti-inflammatory, antitumor, or neuroactive compounds | Serves as a key intermediate in condensation, coupling, or cyclization reactions—e.g., Knoevenagel condensation with aldehydes or nucleophilic substitution with amines |
| Chemical Research | Development of functionalized thiophene derivatives for materials science | Used as a monomer unit for optoelectronic materials or organic semiconductors; processed via polymerization or conjugation extension to yield functional polymers |
Manufacturing Quality Control of Methyl 3-amino-5-phenylthiophene-2-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification relies on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, toluene) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfate Impurity | Ion Chromatography | Quantifies sulfate ions by anion-exchange chromatography with conductivity detection following sample dissolution and dilution. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined standards. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration (600-800 C) and weighing of residual residue. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral centers in solution using sodium D-line (589 nm) at specified concentration and temperature. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a 1% w/v suspension in water using calibrated pH electrode per EP 2.2.3. |
Technical Specifications of Methyl 3-amino-5-phenylthiophene-2-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 3-amino-5-phenylthiophene-2-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 3-amino-5-phenylthiophene-2-carboxylate
Safety Information of Methyl 3-amino-5-phenylthiophene-2-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 3-amino-5-phenylthiophene-2-carboxylate
Industrial Methyl 3-amino-5-phenylthiophene-2-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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