China Factory Direct
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| CAS number | 1001202-16-9 |
| Product name | N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylglycylglycylglycine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protected tetrapeptide intermediate for peptide synthesis, used to construct biologically active peptides containing glycine sequences | Employed as an Fmoc-protected tetraglycine unit in solid-phase peptide synthesis (SPPS), coupled and deprotected via the Fmoc/tBu strategy |
| Biochemical Research | Model peptide segment or enzymatic cleavage substrate for protein structure and function studies | Used as a specific recognition and cleavage substrate for proteases (e.g., trypsin, carboxypeptidase) in enzymology assays |
| Diagnostics Reagent Development | Component of antigenic epitope mimetics or detection probes | Conjugated with fluorescent labels or biotin for use in immunoassays or high-throughput screening platforms |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., deletion sequences, diastereomers) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, MeOH) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of palladium from coupling catalysts using isotope-dilution ICP-MS after microwave-assisted digestion. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC-UV | Measures D/L-glycine content using chiral stationary phase HPLC with UV detection to assess racemization during synthesis. |
| Particle Size Distribution | Laser Diffraction | Determines dry powder particle size distribution by measuring angular variation in laser light scattering intensity. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under controlled temperature and vacuum conditions. |
| pH (1% w/v aqueous solution) | Potentiometric Titration | Determines acidity/basicity using calibrated pH electrode in aqueous suspension; reflects residual protecting group cleavage byproducts. |
| Residual Fmoc Chloride | GC-ECD | Detects trace Fmoc-Cl by gas chromatography with electron capture detection due to high sensitivity for chlorinated compounds. |
| Bioburden | Membrane Filtration | Quantifies viable microbial contamination by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 228–232°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.