China Factory Direct
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| CAS number | 1003-04-9 |
| Product name | Tetrahydrothiophen-3-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibacterial drug intermediates | Used as a starting material in substitution and cyclization reactions |
| Pesticides | Preparation of insecticidal active ingredients | Reacted with haloalkanes under specific catalytic conditions to yield target compounds |
| Fragrances | Synthesis of fragrance additives | Functional group transformation followed by introduction of aromatic moieties for perfumery applications |
| Materials | Production of monomers for functional polymers | Incorporated into polymer chains via polymerization or copolymerization |
| Analytical Chemistry | Used as an analytical reagent | Applied directly for detection or quantitative analysis of certain organic reactions |
| Test Item | Common Test Methods | Method Summary |
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| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with acetonitrile-water or methanol-water as the mobile phase. The UV detector (210–250 nm) measures the peak area of the main component, and content is calculated using an external standard method. Suitable for high-precision quantitative analysis. |
| Purity (Main Component Content) | Gas Chromatography (GC) | Uses a capillary column (e.g., DB-5 or HP-INNOWAX) with an FID detector. Separation is achieved through temperature programming, and content is determined using an external standard method. Suitable for volatile and thermally stable samples. |
| Water Content | Karl Fischer Titration | Utilizes the quantitative reaction of iodine and sulfur dioxide with water in pyridine and methanol. Water content is determined by potentiometric or coulometric methods, with precision down to ppm levels. Considered the gold standard for water determination in organic solvents. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Uses headspace sampling, where the sample is placed in a sealed vial and allowed to equilibrate before injecting the gaseous phase into the GC. FID detector is used to analyze common organic solvent residues such as methanol, ethanol, and acetone, in compliance with ICH Q3C guidelines. |
| Impurity Profile (Organic Impurities) | HPLC-MS / GC-MS | Couples mass spectrometry (LC-MS or GC-MS) to identify unknown impurities (e.g., oxidation products, polymers, unreacted starting materials) based on mass spectral fragmentation. Used for impurity identification and semi-quantitative analysis. |
| Melting Point | Melting Point Apparatus | Measures the melting range using a digital melting point instrument. Compared with literature values (e.g., approximately 35–38°C). Used for preliminary identification and purity assessment; impurities often cause a lower melting point or a broader melting range. |
| Appearance and Color | Visual Inspection + Color Measurement (APHA/Pt-Co) | Visually inspect the transparency and color of the sample, or use a colorimeter to measure the APHA color of a sample solution (e.g., 10% ethanol solution) to determine the presence of pigments or oxidation products. |
| Sulfur Content (Elemental Analysis) | Combustion-Infrared Method / Elemental Sulfur Analyzer | The sample is combusted in a high-temperature oxygen stream to produce SO₂, which is measured by infrared absorption. Used to verify whether the sulfur content matches the theoretical value (theoretical S content ≈ 26.7%). |
| pH Value (Aqueous Solution) | pH Meter | Dissolve the sample in water or buffer (if required), and measure the pH using a calibrated pH meter. Used to assess the presence of acidic or basic impurities (e.g., thiophene acid from hydrolysis). |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion, AAS or ICP-MS is used to measure the content of heavy metals such as lead, cadmium, mercury, and arsenic. Complies with pharmacopeia standards (e.g., USP/EP) for heavy metal control in organosulfur compounds (typically ≤10 ppm). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.505–1.515 |
| Relative Density (20°C/25°C) | 1.12–1.14 g/cm³ |
| Odor | Characteristic sulfurous odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.