1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 10034-20-5 |
| Product name | 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Aminoglycoside drug intermediate for synthesizing antibiotics (e.g., streptomycin derivatives) and antitumor glycoconjugates | Used as a protected form of 2-amino-2-deoxy-D-glucose (D-glucosamine) to provide regioselectivity and chemical stability in solid-phase or solution-phase glycosylation reactions; the hydrochloride salt enhances crystallinity and storage stability |
| Glycochemistry Research | Glycosylamine donor for constructing N-linked oligosaccharides and glycoconjugate vaccine candidates | Participates in glycosylation reactions (e.g., Koenigs–Knorr or triflate activation) after acetyl protection, followed by selective O-acetyl deprotection and conjugation to peptide/protein carriers |
| Bioconjugation Technology | Preparation of fluorescent or biotin-labeled glucosamine probes | Involves derivatization of the free amino group (e.g., with NHS esters), followed by ammonolysis or Zemplén deacetylation to regenerate the amino group for targeted labeling |
Manufacturing Quality Control of 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 205 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; individual impurities reported relative to main peak. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content by stoichiometric reaction. |
| Residual Solvents | GC-FID | Gas chromatographic separation followed by flame ionization detection, calibrated against solvent standards. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and isotopic dilution calibration. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential inflection. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using sodium D-line light source in solution at controlled temperature and concentration. |
| pH (1% w/v aqueous solution) | pH Meter | Direct potentiometric measurement using calibrated pH electrode in freshly prepared aqueous solution. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis using capillary tube method with calibrated thermometer or digital melting point system. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue mass expressed as percentage of original sample. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic bacteria and fungi via membrane filtration followed by culture on TSA and SDA media. |
Technical Specifications of 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 132-136°C |
| Optical Rotation | -35.0 to -39.0° (c=1, H2O) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
Safety Information of 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI
Industrial 1,3,4,6-Tetra-O-acetyl-a-D-glucosamineHCI Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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