7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 100361-18-0 |
| Product name | 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 100361-18-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 100361-18-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 100361-18-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antimicrobial drug intermediate for synthesis of quinolone antibiotics | Chemical synthesis; serves as a key structural unit in cyclization, condensation, and related reactions |
| Pharmaceutical R&D | Lead compound or structural fragment for development of novel antimicrobial agents | Molecular design, structural modification, and activity screening |
| Chemical Research | Organic synthesis intermediate or reference standard | Laboratory-scale synthesis, purification, and analysis |
Manufacturing Quality Control of 100361-18-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using gradient HPLC with diode-array detection for spectral confirmation and relative quantitation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 600-700 C followed by weighing of inorganic residue after sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine size distribution based on light scattering patterns. |
| Bulk Density | USP <616> | Determination of mass per unit volume using standardized tapping and graduated cylinder method. |
| Microbial Limits | Membrane Filtration | Quantitative recovery and enumeration of aerobic microorganisms from solution via filtration and agar culture. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues after microwave-assisted digestion using optical emission spectroscopy. |
Technical Specifications of 100361-18-0
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 100361-18-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 100361-18-0
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Industrial 100361-18-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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