2-Iodo-5-trifluoromethylpyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 100366-75-4 |
| Product name | 2-Iodo-5-trifluoromethylpyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Iodo-5-trifluoromethylpyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Iodo-5-trifluoromethylpyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Iodo-5-trifluoromethylpyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of anticancer, antiviral, and central nervous system agents | Pyridine scaffold introduced via nucleophilic substitution, cross-coupling (e.g., Suzuki, Negishi), or metal-catalyzed coupling reactions |
| Pesticides | Employed as a structural motif in novel insecticides or fungicides | Used as a fluorinated heterocyclic precursor in halogen exchange or catalytic coupling to construct bioactive molecules |
| Chemical Synthesis | Applied as a building block in organic synthesis for constructing complex fluorinated heterocyclic compounds | Utilized in Stille, Sonogashira, or Ullmann coupling reactions to form C–C bonds or incorporate trifluoromethylpyridine motifs |
Manufacturing Quality Control of 2-Iodo-5-trifluoromethylpyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification relies on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., acetone, methanol) by gas chromatography with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni) after acid digestion by inductively coupled plasma mass spectrometry with isotope dilution quantification. |
| Iodine Content | Potentiometric Titration | Quantifies total iodine using sodium thiosulfate titration after oxidative liberation of iodide, monitored by iodide-selective electrode endpoint detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature (700-800 C) incineration and precise weighing of the ash. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size by measuring angular scattering intensity of laser light passed through dispersed sample. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube and controlled heating ramp. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions after sample dissolution and filtration, using suppressed conductivity detection with carbonate eluent. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies low-level genotoxic impurities (e.g., alkyl halides) by gas chromatography coupled to mass spectrometry with SIM mode. |
| Appearance and Color | Visual Inspection and Hazen Color Scale | Assesses physical state and color grade by visual comparison of solution (10 mg/mL in acetonitrile) against platinum-cobalt standards. |
Technical Specifications of 2-Iodo-5-trifluoromethylpyridine
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Iodo-5-trifluoromethylpyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Iodo-5-trifluoromethylpyridine
Safety Information of 2-Iodo-5-trifluoromethylpyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Iodo-5-trifluoromethylpyridine
Industrial 2-Iodo-5-trifluoromethylpyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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