2-CHLOROPYRIMIDINE-5-BORONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1003845-06-4 |
| Product name | 2-CHLOROPYRIMIDINE-5-BORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLOROPYRIMIDINE-5-BORONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLOROPYRIMIDINE-5-BORONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLOROPYRIMIDINE-5-BORONIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for drug molecules, used in the synthesis of kinase inhibitors, antitumor agents, and other therapeutics | Forms carbon–carbon bonds via Suzuki-Miyaura coupling with aryl or heteroaryl halides, introducing the boronic acid group as a key functional moiety |
| Pesticides | Heterocyclic building block for synthesizing novel herbicides or insecticides | Serves as a boronate ester precursor in cross-coupling reactions to construct biologically active molecules containing chloropyrimidine scaffolds |
| Chemical Synthesis | Functionalized building block for constructing nitrogen-containing heterocyclic compounds | Couples aromatic systems via transition-metal-catalyzed reactions (e.g., Pd-catalyzed) to enable rapid synthesis of materials or drug lead compounds |
Manufacturing Quality Control of 2-CHLOROPYRIMIDINE-5-BORONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., THF, toluene, methanol) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine/methanol buffer. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Quantification after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Particle Size Distribution | Laser Diffraction | Measurement of scattered laser light intensity as a function of angle to determine volume-based particle size distribution. |
| Melting Point | DSC | Determination of onset and peak melting temperature via differential scanning calorimetry under controlled nitrogen purge. |
| Organic Volatile Impurities (e.g., benzene, chloroform) | GC-MS | Identification and quantification of genotoxic impurities using gas chromatography coupled with mass spectrometry. |
| Related Substances | HPLC-UV/DAD | Detection and quantification of structurally related impurities (e.g., des-boryl, hydrolyzed, or dimeric species) using gradient HPLC with diode array detection. |
| Bulk Density | ASTM D1895-A | Measurement of mass per unit volume using a calibrated cylinder and tapping apparatus per standard test method. |
| Loss on Drying (LOD) | Thermogravimetric Analysis (TGA) | Mass loss measurement upon controlled heating (e.g., 105 °C, 2 h) under nitrogen flow to determine volatile content. |
| pH of Aqueous Slurry | pH Meter | Measurement of pH in a defined suspension (e.g., 10% w/v in purified water) using a calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of 2-CHLOROPYRIMIDINE-5-BORONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLOROPYRIMIDINE-5-BORONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLOROPYRIMIDINE-5-BORONIC ACID
Safety Information of 2-CHLOROPYRIMIDINE-5-BORONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-CHLOROPYRIMIDINE-5-BORONIC ACID
Industrial 2-CHLOROPYRIMIDINE-5-BORONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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