China Factory Direct
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| CAS number | 100421-52-1 |
| Product name | 2-Thiophenecarboxylicacid,3-fluoro-,methylester(9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antiviral agents (e.g., HCV NS5A inhibitors) | Constructs the active pharmaceutical ingredient scaffold via organic synthesis steps including nucleophilic substitution and coupling reactions |
| Agrochemicals | Intermediate for synthesizing fluorinated thienyl-based insecticides or fungicides | Introduces target structural motifs through reactions such as ester hydrolysis, halogenation, and metal-catalyzed coupling |
| Materials Science | Functional monomer precursor for organic electronic materials (e.g., OLEDs, OFETs) | Polymerizes into conjugated polymers via cross-coupling reactions such as Suzuki and Stille couplings |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by HPLC separation and UV response relative to the main peak. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine-sulfur dioxide reaction in pyridine-methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after combustion in sulfuric acid followed by high-temperature incineration and weighing. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white-light illumination against standard references. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after ignition at 700-800 C in a muffle furnace. |
| pH of Solution | pH Meter | Measures hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.