(R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1004538-34-4 |
| Product name | (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1004538-34-4
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1004538-34-4 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1004538-34-4
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing proteasome inhibitors (e.g., bortezomib analogues) | Introduced as an amino acid derivative into the pyrrolidine scaffold via Fmoc-based solid-phase or solution-phase peptide synthesis |
| Pharmaceuticals | Building block for drug molecules containing a pyrrolidine ring, such as antiviral or antitumor compounds | Serves as a key building block in multistep organic synthesis, undergoing deprotection, coupling, and cyclization to generate active pharmaceutical ingredients |
| Chemical R&D | Organic synthesis intermediate for developing novel heterocyclic compounds | Derivatized via reductive amination, acylation, or substitution reactions for constructing high-throughput screening compound libraries |
Manufacturing Quality Control of 1004538-34-4
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, EtOAc) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based reagent stoichiometrically reacting with water. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Ion | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after anion-exchange column separation. |
| Residual Palladium | ICP-OES | Measures palladium residue from catalytic hydrogenation using inductively coupled plasma optical emission spectroscopy. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Evaluates acidity of a defined aqueous suspension using calibrated pH electrode to assess salt hydrolysis behavior. |
| Loss on Drying | Gravimetric Thermogravimetry | Determines volatile content by measuring weight loss after drying under controlled temperature and vacuum conditions. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dispersed solid sample using angular scattering pattern of laser light. |
Technical Specifications of 1004538-34-4
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +15.0 to +19.0° (c=1, in 1M HCl) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1004538-34-4
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1004538-34-4
Packaging of 1004538-34-4
Industrial 1004538-34-4 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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