China Factory Direct
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| CAS number | 10047-10-6 |
| Product name | methyl norvalinate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral auxiliary; precursor to chiral amino alcohol ligands for asymmetric synthesis | Used to prepare chiral catalysts, such as metal (e.g., Ti, Cu) complexes that catalyze asymmetric alkylation, epoxidation, and related reactions |
| Pharmaceutical R&D | Amino acid derivative intermediate | Converted into pharmaceutical amino acids or their derivatives—such as L-homoserine and L-threonine—via hydrolysis, deprotection, and related steps |
| Organic Synthesis | Chiral resolving agent | Forms diastereomeric salts with racemic carboxylic acids to enable chiral resolution |
| Analytical Chemistry | Chiral chromatographic stationary phase modifier | Introduces chiral recognition moieties onto silica gel surfaces via coupling reactions for HPLC separation of chiral compounds |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and detection of structurally related impurities (e.g., norvaline, methyl ester degradation products) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual methanol, ethyl acetate, or dichloromethane per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection with high sensitivity. |
| Optical Rotation | [α]D Measurement | Determination of specific rotation using a polarimeter at 20 °C and sodium D-line (589 nm), indicating enantiomeric purity and identity. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Incineration at 700–800 °C followed by weighing of inorganic residue to assess inorganic ash content. |
| pH (1% w/v aqueous solution) | pH Potentiometry | Measurement of hydrogen ion activity in aqueous solution using calibrated glass electrode pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to determine D10, D50, D90 values per USP <429>. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 162-166°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Optical Rotation | -15.0° to -19.0° (c=1, in 1M HCl) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.