China Factory Direct
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| CAS number | 10049-83-9 |
| Product name | PYRITHIOXIN DIHYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Treatment of vitamin B6 deficiency; adjunctive therapy for neurological disorders (e.g., peripheral neuritis, polyneuropathy) | Administered orally or via injection as a prodrug of vitamin B6 to support endogenous coenzyme A synthesis |
| Biotechnology | Intermediate in biosynthesis of sulfur-containing vitamin compounds | Used as a catalyst or reagent in organic synthesis reactions, particularly thiolation reactions |
| Chemical Research | Laboratory reagent for studying vitamin B6 metabolic pathways and neurotransmitter synthesis mechanisms | Applied in in vitro cell culture experiments and nutritional intervention studies using animal models |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Pyrithione Acid Content) | Acid-Base Titration with NaOH standard solution | Quantifies pyrithione acid by neutralizing its carboxylic acid group using standardized sodium hydroxide and phenolphthalein or potentiometric endpoint detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS or ICP-OES after acid digestion | Measures trace metal concentrations via plasma-induced atomic emission or mass spectrometry following microwave-assisted nitric/hydrogen peroxide digestion. |
| Residual Solvents (e.g., Ethanol, Acetone) | Gas Chromatography (GC) with FID or HS-GC | Separates and quantifies volatile organic solvents using capillary column GC with flame ionization detection or headspace sampling. |
| Related Substances (Impurities) | Reverse-Phase HPLC with UV detection | Separates and detects structurally related impurities (e.g., unreacted precursors, degradation products) using C18 column and UV absorbance at 254 nm. |
| Water Content | Karl Fischer Coulometric Titration | Determines trace water by electrochemical generation of iodine and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measures inorganic ash content by ignition at 700–800 °C followed by precise weighing of residual non-volatile matter. |
| pH of Aqueous Solution (1% w/v) | Potentiometric pH Measurement | Determines hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension by analyzing angular scattering pattern of laser light. |
| Microbial Limits (Total Aerobic Count, Yeast/Mold) | Membrane Filtration + Plate Count Agar Culture | Quantifies viable microorganisms by filtration, membrane transfer to selective media, and colony enumeration after incubation. |
| Specific Optical Rotation | [α]D at 20 °C | Measures chiral purity and identity via polarimetric detection of rotation angle of plane-polarized light passing through a standardized solution. |
| Melting Point | Capillary Melting Point Apparatus | Determines purity and identity by observing temperature range over which solid transitions to liquid under controlled heating. |
| Sulfate Residue | Barium Sulfate Gravimetric Method or Ion Chromatography | Quantifies sulfate as insoluble BaSO₄ precipitate after precipitation with barium chloride, or via anion-exchange separation and conductivity detection. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Determines chloride ions by titration with silver nitrate using silver indicator electrode or adsorption indicator (e.g., potassium chromate). |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.