2-Bromo-4-iodopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 100523-96-4 |
| Product name | 2-Bromo-4-iodopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-4-iodopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-4-iodopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-4-iodopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serving as a synthetic intermediate in the preparation of anticancer, antiviral, and kinase inhibitor drugs | Constructing complex molecular frameworks via palladium-catalyzed cross-coupling reactions, including Suzuki, Sonogashira, and Buchwald–Hartwig amination |
| Agrochemicals | Synthesizing active ingredients for novel herbicides or insecticides | Functioning as a heterocyclic building block in multistep organic synthesis to incorporate pyridine rings and enhance biological activity |
| Materials Science | Producing organic optoelectronic materials (e.g., OLED emissive layers or electron-transport materials) | Introducing functional groups via halogen–metal exchange or cross-coupling reactions to tune energy levels and charge-carrier mobility |
| Chemical Research | Serving as a versatile synthon for methodology development or ligand design | Enabling regioselective functional group transformations (e.g., sequential coupling) by exploiting differential reactivity of bromo and iodo substituents |
Manufacturing Quality Control of 2-Bromo-4-iodopyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., 2-bromopyridine, 4-iodopyridine, bromo-iodo isomers) using gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) at trace levels using inductively coupled plasma mass spectrometry after acid digestion. |
| Inorganic Halides (e.g., Cl⁻, Br⁻, I⁻) | Ion Chromatography (IC) | Separation and conductivity detection of halide anions; used to assess halogen exchange or hydrolysis by-products. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>; indicates crystallinity and presence of impurities. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline solid) and color intensity compared to platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis | Determination of non-volatile inorganic residue after high-temperature ashing (500–600 °C) and weighing. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light to confirm chiral purity (though compound is achiral, detects chiral contaminants or degradation). |
Technical Specifications of 2-Bromo-4-iodopyridine
| Test Item | Specification |
|---|---|
| Appearance | White Solid |
| ldentification(NMR) | Conforms to structure |
| Purity | ≥95.0% |
| Total of impurities | Maximum 1.00 percent |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-4-iodopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-4-iodopyridine
Packaging of 2-Bromo-4-iodopyridine
Industrial 2-Bromo-4-iodopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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