(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1006376-60-8 |
| Product name | (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antidepressant paroxetine | Prepared via asymmetric synthesis, involving introduction of chloro- and fluoro-substituted phenyl groups |
| Chemical Synthesis | Organic synthesis intermediate | Used to construct complex organic molecules, with further functionalization via nucleophilic substitution or coupling reactions |
Manufacturing Quality Control of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 220 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; (1S)-enantiomer content determined by peak area ratio. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-methanol medium; water reacts stoichiometrically with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification after acid digestion; detection based on mass-to-charge ratio of metal isotopes. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with conductivity detection; chloride identified by retention time and peak area. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities using gradient HPLC with UV detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as solid-to-liquid phase change in a capillary tube under controlled heating. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution; correlates with enantiomeric excess. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard white background under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Mass difference measured before and after high-temperature ashing; reflects non-volatile inorganic residue. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Hydrogen ion activity determined using calibrated glass electrode and reference electrode in aqueous suspension. |
Technical Specifications of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +31.0 to +31.7 deg (c=1, MeOH) |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
Safety Information of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
Industrial (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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