China Factory Direct
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| CAS number | 10075-50-0 |
| Product name | 5-Bromoindole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate in the synthesis of anticancer, antiviral, and central nervous system drugs | Used as a key intermediate in multistep organic synthesis, commonly for constructing indole-based alkaloid structures |
| Pesticide Development | Active ingredient precursor in the synthesis of novel insecticides and fungicides | Bromination via electrophilic substitution, followed by coupling or functional group transformation |
| Polymer Materials | Functional monomer for nitrogen-containing heterocyclic polymers | Participates in polymerization (e.g., Suzuki or Heck coupling) to build conjugated polymer systems |
| Biological Probes | Building block for fluorescent labeling compounds and bioimaging reagents | Coupling reaction to attach 5-bromoindole to fluorophores or targeting moieties |
| Fine Chemicals | Starting material for dyes and catalyst ligands | Used to construct complex aromatic frameworks, with structural modification enabled by palladium-catalyzed coupling reactions |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Typically appears as a white to off-white crystalline powder. |
| Purity (Assay) | High-Performance Liquid Chromatography (HPLC) | Reverse-phase HPLC (e.g., C18 column) with UV detection (commonly set at 220–280 nm) is used. The content of 5-bromoindole is calculated using external standard or area normalization method, effectively separating and quantifying impurities. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR are used to confirm the compound's structure by comparing characteristic peak positions with literature data. |
| Structural Confirmation | Mass Spectrometry (MS) | Molecular ion peak ([M+H]+) is determined using EI-MS or ESI-MS to confirm molecular weight and assist in structural identification. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature using a melting point apparatus. Compare with reference value (literature reports approximately 58–60°C) to assess purity and consistency. |
| Moisture Content | Karl Fischer Titration | Accurately measures water content in the sample; suitable for trace moisture analysis, ensuring storage stability. |
| Residual Solvents | Gas Chromatography (GC) | Detects residual organic solvents from synthesis (e.g., methanol, ethanol, dichloromethane), ensuring compliance with ICH limits. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determines residual levels of heavy metals such as lead, mercury, cadmium, and arsenic to ensure compliance with pharmaceutical or high-purity reagent standards. |
| Related Substances (Impurities) | HPLC Method | Uses gradient elution to separate degradation products or synthetic by-products (e.g., unreacted indole, dibrominated compounds), assessing impurity levels. |
| Sulfated Ash / Residue on Ignition | Sulfated Ashing Method | The sample is ignited at high temperature, and the residue is weighed to evaluate total inorganic impurities; commonly used in raw material quality control. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.