China Factory Direct
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| CAS number | 100750-05-8 |
| Product name | 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Amino acid protecting reagent in solid-phase peptide synthesis (SPPS) | Used as an Nα-protecting group to prevent amino side reactions during peptide chain elongation; the Fmoc group is subsequently removed with piperidine |
| Biochemical Research | Synthesis of fluorescently labeled peptides, enzyme substrates, and structural probes | FMOC-protected phenylalanine residues are introduced under mild basic conditions to construct functional peptides containing aromatic side chains |
| Diagnostics Reagent Development | Preparation of antigen-mimicking peptides and immunoassay reference standards | Coupled to carrier proteins or solid supports via Fmoc-SPPS for use in immunoassay platforms such as ELISA |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies FMOC-DL-phenylalanine by comparing peak area against a certified reference standard using reversed-phase chromatography and UV detection at 265 nm. |
| Related Substances | HPLC-UV | Identifies and quantifies impurities (e.g., FMOC-L-phenylalanine, FMOC-D-phenylalanine, des-FMOC derivatives) via gradient HPLC with UV detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generated electrochemically in a methanol-based reagent. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after charring at 700-800 C and weighing the cooled crucible. |
| Heavy Metals | ICP-OES | Quantifies Pb, Cd, Hg, As, and other heavy metals by plasma excitation and elemental emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 20 C using sodium D-line (589 nm) to assess chiral integrity and enantiomeric composition. |
| Loss on Drying | Thermogravimetric Analysis | Determines volatile content by measuring mass loss after drying at 105 C under vacuum or nitrogen for 2 hours. |
| pH of Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode. |
| Solvent Residues | GC-FID | Detects and quantifies residual solvents (e.g., DMF, dichloromethane, toluene) using capillary GC with flame ionization detection. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and laser diffraction optics. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 98°C - 102°C |
| Optical Rotation | -10.0° to +10.0° (c=1, in DMF) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.