China Factory Direct
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| CAS number | 100784-27-8 |
| Product name | 5-(aminosulfonyl)-3-chloro-1-methyl-1H- pyrazol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Herbicide intermediate | Used in the synthesis of sulfonylurea herbicides, such as nicosulfuron, via nucleophilic substitution or condensation to introduce the sulfonamide moiety |
| Pharmaceuticals | Pharmaceutical intermediate | Serves as a precursor for constructing biologically active molecules containing a pyrazole ring; employed in the synthesis of heterocyclic compounds for developing anti-inflammatory, antimicrobial, or antitumor drug candidates |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection; relative retention times and spectral matching against known impurities. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine, sulfur dioxide, and base in methanol to determine water content by stoichiometric reaction. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of trace heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection after aqueous extraction. |
| Sulfonamide Group Integrity | FTIR Spectroscopy | Identification of characteristic S=O and N-H stretching vibrations in the mid-infrared region to confirm structural integrity. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in suspension using Mie scattering theory and optical detection. |
| Bulk Density | USP <616> Tap Density Test | Determination of tapped density by mechanically tapping a graduated cylinder containing a known mass of sample until volume stabilizes. |
| Melting Point | DSC | Thermal analysis to detect endothermic melting transition and assess purity via depression and peak shape. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after high-temperature ashing (700-800 C) to determine inorganic ash content. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms by filtration, membrane transfer to culture media, and colony counting after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.