(R)-1-CBZ-3-PYRROLIDINOL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 100858-33-1 |
| Product name | (R)-1-CBZ-3-PYRROLIDINOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-CBZ-3-PYRROLIDINOL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-CBZ-3-PYRROLIDINOL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-CBZ-3-PYRROLIDINOL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral intermediates | Used in the synthesis of protease inhibitors, such as antiretroviral drugs |
| Pharmaceutical R&D | Organic synthesis building blocks | Participates in multistep synthesis as a pyrrolidine derivative containing a chiral hydroxyl group and a protected amino group |
| Fine chemicals | Chiral reagent preparation | Converted into other chiral catalysts or ligands via deprotection or functional group transformation |
Manufacturing Quality Control of (R)-1-CBZ-3-PYRROLIDINOL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase and UV detection, resolving (R)-enantiomer from potential (S)-impurity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to quantify water via stoichiometric reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for quantification of common solvents (e.g., ethyl acetate, methanol, toluene). |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, based on atomic emission intensity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by sulfuric acid treatment and weighing of residual inorganic ash. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and concentration. |
| Related Substances | HPLC-UV (Forced Degradation) | Stability-indicating method with stressed conditions (acid, base, oxidation, heat) to detect and quantify structurally related impurities. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via visual observation of solid-to-liquid phase change in capillary tube. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting. |
| pH of Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous or aqueous-organic solution. |
Technical Specifications of (R)-1-CBZ-3-PYRROLIDINOL
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Optical Rotation | -21 to -25° (c=1, in CHCl3) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-CBZ-3-PYRROLIDINOL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-CBZ-3-PYRROLIDINOL
Packaging of (R)-1-CBZ-3-PYRROLIDINOL
Industrial (R)-1-CBZ-3-PYRROLIDINOL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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