China Factory Direct
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| CAS number | 101084-39-3 |
| Product name | 3-BROMO-2-METHOXYBENZOIC ACID 97 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antiplatelet drug ticagrelor | (S)-3-Bromo-2-methoxybenzoic acid is prepared via chiral resolution or asymmetric synthesis, followed by condensation with chloroacetyl chloride and subsequent amination/cyclization to construct the triazolopyrimidine core |
| Pesticide R&D | Structural modification unit for novel insecticides and plant growth regulators | Serves as a bromo/methoxy bifunctional aromatic building block in Suzuki coupling, Ullmann condensation, and other reactions to construct heterocycle-containing bioactive molecular scaffolds |
| Organic Synthesis | Multifunctional aromatic carboxylic acid derivative for constructing complex molecular frameworks | Carboxyl group is converted to acyl chlorides, esters, or amides; the aryl bromide participates in transition-metal-catalyzed cross-coupling reactions (e.g., Pd-catalyzed Heck and Stille reactions) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, dichloromethane) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element detection of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 750 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or optically as solid-to-liquid phase change under controlled heating rate. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration and wavelength. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern to calculate volume-based particle size distribution in dispersed sample. |
| Bulk Density | USP <616> Tap Density Method | Determination of mass per unit volume after mechanical tapping of a known powder mass in a calibrated cylinder. |
| Microbial Limits | Membrane Filtration | Filtration of sample solution through sterile membrane, followed by incubation on selective agar media for aerobic bacteria and fungi enumeration. |
| Test Item | Specification |
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| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 125–129 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.