1-(2-Fluorophenyl)piperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1011-15-0 |
| Product name | 1-(2-Fluorophenyl)piperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(2-Fluorophenyl)piperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(2-Fluorophenyl)piperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(2-Fluorophenyl)piperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for central nervous system (CNS) drugs, used in the synthesis of antipsychotics (e.g., aripiprazole analogues) and 5-HT1A receptor modulators | Serves as a key structural unit in multistep coupling reactions (e.g., Suzuki or Ullmann couplings), followed by acylation, alkylation, or condensation to construct the target molecular scaffold |
| Pharmaceuticals | Core structural motif for modifying antidepressant and anxiolytic candidate compounds | Introduces pharmacophores via N-alkylation, N-acylation, or condensation with aldehydes/ketones to optimize physicochemical properties and target binding affinity |
| Agrochemicals | Fluorinated piperazine structural module in molecular design of novel insecticides/fungicides | Used to build heterocyclic side chains with enhanced lipophilicity and metabolic stability, typically combined with triazole or pyrimidine core structures for structure–activity relationship (SAR) studies |
| Materials Science | Functionalization unit for hole-transport materials in organic light-emitting diodes (OLEDs) | Introduced as an electron-donating group into carbazole or triphenylamine derivatives via Suzuki coupling or Buchwald–Hartwig amination to enable molecular engineering |
Manufacturing Quality Control of 1-(2-Fluorophenyl)piperazine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine/methanol medium to determine water by stoichiometric reaction. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for trace-level quantification of elements such as Pb, Cd, Hg, and As based on elemental mass-to-charge ratios. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C with sodium D-line (589 nm) to assess chiral purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis via capillary tube method observing solid-to-liquid transition range under controlled heating rate. |
| pH of Aqueous Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after ignition at 600 C in a muffle furnace, indicating non-volatile impurities. |
| Appearance | Visual Inspection | Subjective assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
Technical Specifications of 1-(2-Fluorophenyl)piperazine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 58.0–62.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(2-Fluorophenyl)piperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(2-Fluorophenyl)piperazine
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Industrial 1-(2-Fluorophenyl)piperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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