China Factory Direct
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| CAS number | 1012-05-1 |
| Product name | DL-Homophenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antihypertensive drugs (e.g., phenylalanine-derived ACE inhibitors) | Purified following chiral resolution or asymmetric synthesis; serves as a key chiral building block in peptide coupling reactions |
| Pharmaceuticals | Research-grade reference standard for developing biomarker detection methods in metabolic disorders (e.g., hyperphenylalaninemia) | Used as external or internal calibration standard in quantitative analysis by high-performance liquid chromatography (HPLC) or liquid chromatography–mass spectrometry (LC-MS) |
| Food Science | Amino acid nutritional fortification research component (not intended for direct food use; limited to laboratory formulation evaluation) | Co-formulated with other branched-chain and aromatic amino acids; evaluated for bioavailability using in vitro digestion models and cellular uptake assays |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC with UV detection | Quantitative determination using reversed-phase HPLC and UV absorbance at 200-220 nm relative to a certified reference standard. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral DL-phenylglycine in solution at specified concentration and wavelength (e.g., sodium D line). |
| Loss on Drying | Gravimetric thermogravimetry | Mass loss measured after drying sample at 105 C for 2 hours under atmospheric pressure. |
| Residue on Ignition | Sulfated ash gravimetry | Mass of non-volatile inorganic residue remaining after high-temperature incineration following sulfuric acid treatment. |
| Chloride Impurity | Potentiometric titration with silver nitrate | Titration with AgNO3 using silver indicator electrode; endpoint detected by potential jump due to AgCl precipitation. |
| Sulfate Impurity | Turbidimetric analysis with barium chloride | Formation of BaSO4 precipitate in acidic medium, quantified by measuring turbidity at 420 nm. |
| Heavy Metals (as Pb) | Colorimetric dithizone method | Reaction with dithizone in alkaline medium to form colored metal-dithizone complex, measured spectrophotometrically. |
| Iron Impurity | UV-Vis spectrophotometry with 1,10-phenanthroline | Formation of orange-red Fe(II)-phenanthroline complex at pH 3-9, measured at 510 nm. |
| Related Substances | HPLC with gradient elution | Separation and quantification of structurally related impurities (e.g., phenylglycine isomers, degradation products) using validated HPLC method. |
| Water Content | Karl Fischer titration | Electrochemical titration with iodine-based reagent; water reacts stoichiometrically to generate endpoint current change. |
| pH of Aqueous Solution | Potentiometric pH measurement | Determination using calibrated glass electrode in 1% w/v aqueous solution at 25 C. |
| Microbial Limits | Membrane filtration and colony counting | Enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial compendia. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 278-282°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +/- 0.5° (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.