5-Bromo-2-fluoro-3-Pyridinol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1012084-53-5 |
| Product name | 5-Bromo-2-fluoro-3-Pyridinol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Bromo-2-fluoro-3-Pyridinol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Bromo-2-fluoro-3-Pyridinol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Bromo-2-fluoro-3-Pyridinol
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key structural motif for synthesizing kinase inhibitor-based anticancer drugs (e.g., EGFR inhibitors) | Introducing aryl or amino side chains via Suzuki coupling or Buchwald–Hartwig amination |
| Agrochemical R&D | Nitrogen-containing heterocyclic pharmacophore in novel insecticides and herbicides | Participating in nucleophilic substitution or metal-catalyzed carbon–heteroatom bond formation to modify pyridine rings for optimized biological activity |
| Organic Synthesis | Multifunctional heterocyclic building block for constructing complex fluorinated nitrogen-containing heteroaromatics | Undergoing lithium–halogen exchange followed by addition to aldehydes/ketones, or serving as a substrate for selective C–H functionalization |
Manufacturing Quality Control of 5-Bromo-2-fluoro-3-Pyridinol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., regioisomers, dehalogenated by-products) using gradient HPLC and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., methanol, acetone, DMF) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol medium. |
| Heavy Metals | ICP-MS | Measures trace-level toxic elements (Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against defined standards under controlled lighting conditions. |
| Bulk Density | Tap Density Tester | Measures mass per unit volume after standardized tapping; indicates powder flow and handling characteristics. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution by analyzing angular scattering pattern of laser beam passing through dispersed particles. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
Technical Specifications of 5-Bromo-2-fluoro-3-Pyridinol
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 124–128°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Bromo-2-fluoro-3-Pyridinol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Bromo-2-fluoro-3-Pyridinol
Packaging of 5-Bromo-2-fluoro-3-Pyridinol
Industrial 5-Bromo-2-fluoro-3-Pyridinol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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