3-(Trifluoromethoxy)benzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1014-81-9 |
| Product name | 3-(Trifluoromethoxy)benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeElectronic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-(Trifluoromethoxy)benzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-(Trifluoromethoxy)benzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-(Trifluoromethoxy)benzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor agents (e.g., key intermediate for the Bcl-2 inhibitor ABT-199/venetoclax) | Construction of benzimidazole or heterocyclic core structures via multistep reactions including acid chloride formation, aminolysis, and coupling |
| Agrochemicals | Synthesis intermediate for high-efficacy insecticides (e.g., flupyradifurone) | Introduction of the 3-(trifluoromethoxy)benzoyl moiety via esterification, nitration, reduction, diazotization, and Sandmeyer reaction |
| Materials Science | Building block for hole-transport materials in organic light-emitting diodes (OLEDs) | Conversion of 3-(trifluoromethoxy)benzoic acid into aryl phosphonate esters or carbazole derivatives via Suzuki or Ullmann coupling |
| Liquid Crystal Materials | Side-chain modification component for high-performance liquid crystal monomers | Esterification of the acid chloride with hydroxyl-containing liquid crystal cores (e.g., biphenol derivatives) to introduce the strongly electron-withdrawing trifluormethoxy group for mesophase behavior modulation |
Manufacturing Quality Control of 3-(Trifluoromethoxy)benzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection; impurities quantified relative to main peak using response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other heavy metals after acid digestion, using atomic emission spectroscopy at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary method per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of crystalline solid against defined standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry powder form using light scattering principles and Mie theory-based analysis. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized sodium hydroxide solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after ignition at 600 C for 30 minutes, per USP <281>. |
Technical Specifications of 3-(Trifluoromethoxy)benzoic acid
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 124.0–127.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-(Trifluoromethoxy)benzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-(Trifluoromethoxy)benzoic acid
Safety Information of 3-(Trifluoromethoxy)benzoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-(Trifluoromethoxy)benzoic acid
Industrial 3-(Trifluoromethoxy)benzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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