China Factory Direct
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| CAS number | 101987-86-4 |
| Product name | ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate in the synthesis of antiviral drugs | Synthesized via esterification and fluorination reactions |
| Agrochemical Industry | Used in the synthesis of high-efficacy insecticides or herbicides | Chlorine and fluorine groups introduced via electrophilic substitution reactions |
| Materials Science | Precursor for functional materials | High-molecular-weight materials prepared via condensation or polymerization reactions |
| Chemical Research | Employed in studies of organic synthetic methodologies | Serves as a model compound in diverse organic reaction experiments |
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Appearance and Physical Form | Visual Inspection + Physical Property Determination | Observe sample color and state (typically a colorless to pale yellow liquid or low-melting solid), measure melting point or boiling range, and evaluate compliance with specifications (e.g., clear, free of suspended particles). |
| Assay (Main Component Purity) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with acetonitrile-water or methanol-water as mobile phase and UV detection (wavelength 210–254 nm). Calculate the percentage of main component peak area using external or internal standard method; typically requires ≥98.0%. |
| Residual Solvents | Gas Chromatography (GC) | Employ headspace or direct injection, using DB-624 or HP-INNOWAX column with FID detector. Detect residual solvents such as ethanol, ethyl acetate, and dichloromethane according to ICH Q3C guidelines, ensuring compliance with permissible limits. |
| Water Content | Karl Fischer Titration | Determine trace moisture using coulometric or volumetric Karl Fischer reagent. Control water content ≤0.5% to prevent hydrolysis or stability issues. |
| Related Substances (Impurity Profile) | HPLC with Gradient Elution | Use gradient elution to separate the main component from potential degradation products (e.g., hydrolysis products, dechlorinated impurities, dimers), detect at 220 nm. Total impurities typically controlled ≤1.0%, with individual impurities ≤0.5%. |
| Chlorine Content | Combustion Ion Chromatography (CIC) or Oxygen Bomb Combustion + Ion Chromatography | Fully combust the sample and absorb the products in alkaline solution, then determine chloride ion concentration by ion chromatography. Compare with theoretical value to verify presence and content of chlorine atoms as per molecular formula (C₁₀H₆ClF₄O₃). |
| Fluorine Content | Ion-Selective Electrode (ISE) or ICP-MS | After alkali fusion or oxygen bomb combustion, measure F⁻ concentration using fluoride ion-selective electrode, or determine total fluorine content via Inductively Coupled Plasma Mass Spectrometry (ICP-MS), verifying stoichiometric accuracy of four fluorine atoms. |
| Melting Point / Boiling Point | Melting Point Apparatus / Vacuum Distillation | Determine melting point by capillary method (if solid) or boiling point range by vacuum distillation as physical constants for identification. Typical boiling point range is approximately 180–200°C at 10 mmHg. |
| Optical Rotation (if applicable) | Refractometer or Polarimeter | If the molecule is chiral or contains chiral centers (this compound has none; test generally not required), used to confirm optical purity. This substance is achiral and usually not tested. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopeial or ICH Q3D limits (e.g., Pb ≤10 ppm). |
| pH Value (if in solution) | pH Meter | If dissolved in solvent (e.g., ethanol), measure pH to ensure absence of acidic or basic contaminants. As this compound is a neutral ester, pH should be close to 7. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.