China Factory Direct
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| CAS number | 10199-89-0 |
| Product name | 4-Chloro-7-nitrobenzofurazan |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Fluorescent labeling reagent | Used for fluorescent derivatization analysis of proteins, amino acids, and biomolecules, commonly applied in high-performance liquid chromatography (HPLC) |
| Biochemistry | Biomolecule detection | Reacts with primary amine groups to generate highly fluorescent products, suitable for quantitative analysis of trace biomolecular samples |
| Environmental monitoring | Pollutant analysis | Employed as a fluorescent probe for detecting specific organic compounds in environmental samples |
| Food safety | Food component analysis | Applied for fluorescent labeling and detection of amino acids and amine compounds in food |
| Analytical chemistry | Analytical reagent | Used as a derivatization reagent in spectroscopic and chromatographic analysis to enhance detection sensitivity |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Inspect color, physical state, and presence of impurities by visual observation. 4-Chloro-7-nitrobenzofurazan (NBD-Cl) is typically a yellow to orange-yellow crystalline powder. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Detect the main peak area using a UV detector (typically at λ = 254 nm or around 340 nm) to calculate sample purity and assess impurity levels. |
| Assay | UV-Visible Spectrophotometry (UV-Vis) or HPLC External Standard Method | Determine concentration based on the characteristic absorbance of NBD-Cl at a specific wavelength (e.g., 340 nm) using a calibration curve; or perform quantitative analysis of the main component via HPLC with an external standard. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, then calculate the percentage weight loss to evaluate moisture and volatile content. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range from initial melting to complete melting using a melting point apparatus. The typical melting point of NBD-Cl is approximately 90–93°C, used to assess purity and consistency. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC equipped with an FID detector to perform qualitative and quantitative analysis of potentially residual organic solvents (e.g., acetone, dichloromethane). |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Separate the main component from potential degradation products or synthesis by-products using a gradient elution program. Coupling with mass spectrometry (LC-MS) can assist in structural identification, enabling control of individual impurity limits. |
| pH (if prepared as a solution) | pH Meter Method | Prepare a solution of specified concentration (e.g., 1%) in water and measure its acidity or alkalinity using a calibrated pH meter to evaluate stability and suitability. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.