China Factory Direct
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| CAS number | 10224-72-3 |
| Product name | DIMETHYL 1,1-CYCLOBUTANEDICARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Intermediate for synthesizing cyclobutane derivatives and pharmaceutical molecules containing a cyclobutyl group | Functional group transformation following transesterification or hydrolysis |
| Pharmaceutical R&D | Building block for constructing cyclobutyl moieties in candidate antiviral and anticancer drugs | Used as a cyclobutyl source in coupling or nucleophilic substitution reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID | Quantification by gas chromatography with flame ionization detection using an internal standard and calibration curve. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of water with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents using headspace GC with FID detection. |
| Heavy Metals | ICP-OES | Multi-element determination of metallic impurities by inductively coupled plasma optical emission spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Acidity (as HCl) | Acid-Base Titration | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Measurement of yellowness index against platinum-cobalt standards using a colorimeter or spectrophotometer at 430 nm. |
| Density | Digital Density Meter | Determination of mass per unit volume at specified temperature using oscillating U-tube principle. |
| Refractive Index | Refractometry | Measurement of light bending angle at air-sample interface using Abbe refractometer calibrated with distilled water. |
| Peroxide Value | Iodometric Titration | Oxidation of iodide to iodine by peroxides, followed by titration with standardized sodium thiosulfate solution. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile inorganic residue after high-temperature ashing of sample in a muffle furnace. |
| Particle Size Distribution | Laser Diffraction | Size analysis of solid particles in suspension by measuring angular variation in laser light scattering intensity. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Melting Point | 124-128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.