China Factory Direct
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| CAS number | 102297-41-6 |
| Product name | N-BOC-3-AMINOMETHYLPYRIDINE 97 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in drug synthesis for preparing active pharmaceutical ingredients (APIs), such as kinase inhibitors or neuroactive agents | BOC protection of amino groups in organic synthesis, followed by deprotection and subsequent functional group transformations along the synthetic route |
| Research | Building block in chemical research for synthesizing complex heterocyclic compounds or molecular probes | Amidation, alkylation, or coupling reactions (e.g., Suzuki coupling) at laboratory scale to explore novel reactions or bioactive molecules |
| Biochemistry | Preparation of proteasome inhibitors or targeted molecules for enzyme activity studies | Introduction of BOC-protected amino groups via solid-phase or solution-phase synthesis for preparing peptide mimetics or small-molecule inhibitors |
| Materials Science | Precursor for functionalized molecules used in ligand synthesis or surface-modified materials | Covalent attachment or functionalization modification via amino groups during polymer or nanomaterial synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., de-BOC product, residual pyridine, BOC-anhydride) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization detection (or MS confirmation) to quantify residual solvents (e.g., dichloromethane, ethyl acetate, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of toxic elements (e.g., Pb, Cd, Hg, Ni) after acid digestion, based on elemental emission or mass spectrometric detection. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of Pd (common catalyst residue from synthesis) following microwave-assisted acid digestion and isotopic analysis. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation using a polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity (if applicable to stereoisomer). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; used for identity and purity assessment (sharpness and range consistent with reference standard). |
| Residual Chlorides | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification (IC) or argentometric titration (potentiometric endpoint) to detect chloride from synthesis intermediates or workup. |
| Appearance & Color | Visual Inspection / Hazen/APHA Color Scale | Subjective assessment against water or platinum-cobalt standards under controlled lighting to detect discoloration or particulates. |
| pH of Aqueous Suspension | pH Meter (10% w/v suspension in water) | Measurement of surface proton activity indicating acidic/basic impurities or hydrolytic degradation products. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values relevant to handling, dissolution, and formulation performance. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.