China Factory Direct
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| CAS number | 120-29-6 |
| Product name | Tropine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing atropine and related alkaloid drugs | Used as a key chiral building block in cyclic esterification and amination reactions |
| Organic Synthesis | Chiral reagent and raw material for asymmetric synthesis | Applied in stereoselective synthesis of nitrogen-containing heterocyclic compounds |
| Pesticides | Intermediate for plant growth regulators | Involved in synthesizing physiologically active pyrrolidine derivatives |
| Fine Chemicals | Specialty solvent and reaction auxiliary | Added as a stabilizing additive in highly selective catalytic hydrogenation processes |
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of tropine and compare it with the reference spectrum to confirm the consistency of molecular structural features, such as hydroxyl and tertiary amine groups. |
| Identification Test | Thin Layer Chromatography (TLC) | Develop the sample and reference standard under identical conditions, then compare their Rf values and staining behavior to preliminarily identify the presence of tropine. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-phosphate buffer solution) for gradient or isocratic elution. Quantify tropine content using a UV detector (typically at 210–220 nm), offering high sensitivity and good reproducibility. |
| Content Determination | Non-aqueous Titration | Perform titration in a non-aqueous solvent (e.g., glacial acetic acid) using perchloric acid as titrant, with crystal violet or potentiometric endpoint indication. Quantify based on the basicity of the tertiary amine group in tropine. |
| Impurity Testing / Related Substances | High-Performance Liquid Chromatography (HPLC) | Employ a gradient elution program to separate and detect possible synthetic intermediates, degradation products, or other organic impurities in tropine. Typically quantified using either the main component self-reference method or area normalization. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant-Pressure Drying Method | Dry the sample to constant weight at a specified temperature (e.g., 105°C) and measure the percentage loss in mass due to moisture or volatile components, assessing its drying status. |
| Residual Ash | High-Temperature Incineration Method | Incinerate the sample at high temperature (typically 700–800°C) and determine the weight of residual inorganic matter (ash), used to control the level of inorganic impurities. |
| Optical Rotation | Polarimeter Method | Tropine has a chiral center; measure its optical rotation at a specific wavelength (typically sodium D line, 589 nm) and concentration to verify optical purity and configurational consistency. |
| pH Value | pH Meter Method | Prepare a solution of tropine at a defined concentration and measure its pH using a calibrated pH meter, reflecting its acidity/alkalinity and potential acidic/basic impurities. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with a capillary column and FID detection to analyze and quantify organic solvents potentially remaining from production processes (e.g., methanol, acetone, dichloromethane). |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 47–49°C |
| Optical Rotation | +3.5° to +4.5° (c=1 in chloroform) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.